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Research GBB Molecular Cell Biology OEPM

Program

Thursday October 25th

8.15 – 9.00 Registration, mounting of Posters

9.00 – 9.10 Welcome Address  Ida van der Klei

1st SESSION PEROXISOMAL PROTEIN SORTING

Chair: Einat Zalckvar

9.10 - 9.30   Noa Dahan, Weizmann Institute of Science, Israel Peroxisomal localized translation; an additional protein targeting mechanism in S. cerevisiae .
9.30 - 9.50 Ana G. Pedrosa, University of Porto, Portugal Monoubiquitinated PEX5 is a natural substrate of the AAA ATPases PEX1 and PEX6.
9.50 - 10.10   Rebecca Brinkmeier, Ruhr-Universität Bochum, Germany The deubiquitination of the PTS1-import receptor Pex5p is required for peroxisomal matrix protein import.
10.10- 10.30 Sven Fischer , University of Freiburg, Germany Phosphorylation of the peroxisomal matrix protein import receptor Pex5p regulates cargo-binding affinity .

10:30 – 11:00 | Coffee Break

11.00-11.20 Mira Rosenthal, Weizmann Institute of Science, Israel Uncovering targeting priority to peroxisomes using a new targeting competition assay.
11.20-11.40 Thorsten Stehlik, Philipps University of Marburg, Germany

The protein phosphatase Ptc5p from S. cerevisiae transits from mitochondria to peroxisomes.

2nd SESSION PEROXISOME DYNAMICS AND TRANSPORT

Chair: Stephan Kemp

11.40-12.00 Saugat Pokhrel, University of Hamburg, Germany Molecular Characterization of a Novel Prenylated Small GTPase of Arabidopsis Peroxisomes.
12.00-12.20 Josiah Passmore, University of Exeter, UK Modelling Peroxisome Dynamics in Health and Disease.
12:20 – 15:20 | Poster session with Lunch Buffet

15.20-15.40 Lennart Charton, Heinrich-Heine-Universität Düsseldorf, Germany Identification of a novel peroxisomal transport protein involved in heat stress response of Arabidopsis thaliana.
15.40-16.00 Hien Bui, University of Helsinki, Finland Age-selective segregation of peroxisomes during stem cell division is mediated by the mitotic spindle.
16.00-16.20 Fei Wu, University of Groningen, The Netherlands The role of the ER-localized Pex23 and Pex24 family proteins in peroxisome biogenesis in Hansenula polymorpha.
16.20-17.00 The Peroxisome Research Award
Joe Costello, University of Exeter The role of ACBD4 and ACBD5 in ER-peroxisome interactions

17:00 – 18:30 | Poster Session

18.30 Dinner Buffet

Friday October 26th

3rd SESSION PEROXISOMES IN HEALTH AND DISEASE

Chair: Francesca di Cara

9.00 – 9.20 Ann-Britt Schäfer, Ruhr-Universität Bochum, Germany Glycosome biogenesis in trypanosomes: Identification of new drugs and drug targets.
9.20 – 9.40 Juan Francisco Rodríguez-Alcázar, Institut für Angeborene Immunität, Biomedizinisches Zentrum, Bonn, Germany Peroxisomes modulate inflammation at the level of the NLRP3 inflammasome.
9.40-10.00 Quentin Raas, Université de Bourgogne, France ABCD1 and ABCD2 deficiency in microglia: Towards a better understanding of the physiopathogenesis of X-ALD.
10.00-10.20 Catherine Argyriou, McGill University, Canada Diosmetin recovers peroxisome functions in Zellweger Spectrum Disorder fibroblasts in a mutation-specific
10.20-10.40   Yannick Das, KU Leuven, Belgium Retinal degeneration in a mouse model with peroxisomal β-oxidation deficiency.


10:40 – 11:00 | Coffee Break

4th session PEROXISOMAL PROTEIN DEGRADATION AND AUTOPHAGY

Chair: Peter Kim

11.00-11.20 Victoria Riccio, University of Toronto, Canada USP30 maintains basal peroxisome abundance by regulating pexophagy.
11.20-11.40 Daniel Schwerter, Ruhr-University Bochum, Germany Functional Characterization of Peroxisomal Msp1p/ATAD1.
11.40-12.00 Srishti Devarajan, University of Groningen, The Netherlands Insights into a novel ubiquitin-dependent protein quality control pathway at the peroxisomal membrane.
12.00-12.20 Tanja Eberhart, ETH Zürich, Institute for Molecular Health Sciences, Zürich, Switzerland Exploring the impact of reduced peroxisome abundance on ccRCC tumorigenesis.
12.20-12.40 Nick Demers, University of Toronto, Canada New players in the selective autophagy of peroxisomes, the role of PEX13.

12:40 – 15:00 | Poster session with Lunch Buffet

5th SESSION SIGNALLING AND REGULATION

Chair: Nicole Linka

15.00-15.20 Matt Anderson-Baron, University of Alberta, Canada Peroxisomal Components Function to Regulate Lipolysis at the Lipid Droplet Surface.
15.20-15.40 Elisabath Rackles, Ludwig-Maximilian-University Munich, Germany A peroxisomal retrograde signaling is induced upon peroxisomal stress in Caenorhabditis elegans.
15.40 -16.00 Francesca Di Cara, University of Alberta, Canada Dysfunctional peroxisomes compromise intestinal homeostasis by increased cell death and Tor-dependent autophagy.
16.00-16.20 Julia Sellin, University of Bonn, Germany Lipid metabolism dysregulation in the absence of peroxisomes.
16.20-16.40 Celien Lismont, Univeristy of Leuven, Belgium PXMP2 and PEX11B are not essential for hydrogen peroxide permeation across the peroxisomal membrane.

    16.40 | Closure

Last modified:19 October 2018 12.57 p.m.