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About us Practical matters How to find us prof. dr. W. (Wijnand) Helfrich

University Medical Center Groningen

prof. dr. W. (Wijnand) Helfrich

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Faculty of Medical Sciences

Telephone:

+31 50 361 3733

E-mail:

w.helfrich umcg.nl

Homepage ORCID Research Portal

Publications

Visible Light Control over the Cytolytic Activity of a Toxic Pore-Forming Protein

Volarić, J., van der Heide, N. J., Mutter, N. L., Samplonius, D. F., Helfrich, W., Maglia, G., Szymanski, W. & Feringa, B. L., 16-Feb-2024, In: ACS chemical biology. 19, 2, p. 451–461 11 p., 3c00640.

Research output: Contribution to journal › Article › Academic › peer-review

A Novel Bispecific Antibody for EpCAM-Directed Inhibition of the CD73/Adenosine Immune Checkpoint in Ovarian Cancer

Ploeg, E. M., Britsch, I., van Wijngaarden, A. P., Ke, X., Hendriks, M. A. J. M., Samplonius, D. F. & Helfrich, W., Jul-2023, In: Cancers. 15, 14, 15 p., 3651.

Research output: Contribution to journal › Article › Academic › peer-review

Applications of Anti-Cytomegalovirus T Cells for Cancer (Immuno)Therapy

Britsch, I., van Wijngaarden, A. P. & Helfrich, W., Aug-2023, In: Cancers. 15, 15, 22 p., 3767.

Research output: Contribution to journal › Review article › peer-review

Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR

Ploeg, E. M., Samplonius, D. F., Xiong, X., Ke, X., Hendriks, M. A. J. M., Britsch, I., Van Wijngaarden, A. P., Zhang, H. & Helfrich, W., 21-Sept-2023, In: Journal for immunotherapy of cancer. 11, 9, 15 p., e006837.

Research output: Contribution to journal › Article › Academic › peer-review

Novel Fab-peptide-HLA-I fusion proteins for redirecting pre-existing anti-CMV T cell immunity to selective eliminate carcinoma cells

Britsch, I., van Wijngaarden, A. P., Ke, X., Hendriks, M. A. J. M., Samplonius, D. F., Ploeg, E. M. & Helfrich, W., 2023, In: OncoImmunology. 12, 1, 2207868.

Research output: Contribution to journal › Article › Academic › peer-review

A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Helbert, H., Ploeg, E. M., Samplonius, D. F., Blok, S. N., Antunes, I. F., Böhmer, V. I., Luurtsema, G., Dierckx, R. A. J. O., Feringa, B. L., Elsinga, P. H., Szymanski, W. & Helfrich, W., 3-Mar-2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 11 p., 3.

Research output: Contribution to journal › Article › Academic › peer-review

Impact of cumulative complications on 1-year treatment-related healthcare costs in patients with colorectal peritoneal metastases undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy

van der Zant, F. A., Kooijman, B. J. L., Hentzen, J. E. K. R., Helfrich, W., Ploeg, E. M., van Ginkel, R. J., van Leeuwen, B. L., Been, L. B., Klaase, J. M., Hemmer, P. H. J., van der Hilst, C. S. & Kruijff, S., 2-Sept-2022, In: BJS open. 6, 5, 9 p., zrac109.

Research output: Contribution to journal › Article › Academic › peer-review

Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles

Xiong, X., Ke, X., Wang, L., Lin, Y., Wang, S., Yao, Z., Li, K., Luo, Y., Liu, F., Pan, Y., Yeung, S.-C. J., Helfrich, W. & Zhang, H., 2022, In: Journal of Extracellular Vesicles. 11, 8, 19 p., e12243.

Research output: Contribution to journal › Article › Academic › peer-review

Bispecific antibody CD73xEpCAM selectively inhibits the adenosine-mediated immunosuppressive activity of carcinoma-derived extracellular vesicles

Ploeg, E. M., Ke, X., Britsch, I., Hendriks, M. A. J. M., Van der Zant, F. A., Kruijff, S., Samplonius, D. F., Zhang, H. & Helfrich, W., 28-Nov-2021, In: Cancer letters. 521, p. 109-118 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRP alpha axis

Hendriks, M. A. J. M., Britsch, I., Ke, X., van Wijngarden, A. P., Samplonius, D. F., Ploeg, E. M. & Helfrich, W., 20-Nov-2021, In: OncoImmunology. 10, 1, 14 p., 2005344.

Research output: Contribution to journal › Article › Academic › peer-review

All (123) publications

Press/media

Sponsorloop Tocht om de Noord brengt ruim 5.000 euro op voor onderzoek bestrijding kanker

Helfrich, W.

23/09/2023

Press/Media: Public Engagement Activities › Popular

Prof. Wijnand Helfrich van het UMCG over samenwerking Fight Cancer & Tocht om de Noord

Helfrich, W.

23/08/2023

Press/Media: Public Engagement Activities › Professional

Wandelklassieker Tocht om de Noord wil blijvend kankeronderzoek in Groningen steunen

Helfrich, W.

02/08/2023

Press/Media: Public Engagement Activities › Popular

Rotaryclub Uithuizen – Het Hogeland schenkt €10.000 aan UMCG Kanker Researchfonds

Helfrich, W.

14/06/2023

Press/Media: Other › Popular

All (4) press/media

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