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University Medical Center Groningen

M. (Matthijs) Luxen

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Faculteit Medische Wetenschappen/UMCG

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m.luxen umcg.nl

ORCID Research Portal

Publicaties

Heterogeneous Patterns of Endothelial NF-κB p65 and MAPK c-Jun Activation, Adhesion Molecule Expression, and Leukocyte Recruitment in Lung Microvasculature of Mice with Sepsis

Wang, Z., Dayang, E.-Z., Zwiers, P. J., Garcia, M. L. H., Luxen, M., van Meurs, M., Moser, J., Kamps, J. A. A. M. & Molema, G., 26-jul.-2024, In: Biomedicines. 12, 8, 22 blz., 1672.

Onderzoeksoutput › › peer review

Recruitment of neutrophils in glomeruli in early mouse sepsis is associated with E-selectin expression and activation of endothelial NF-κB and MAPK pathways

Wang, Z., Dayang, E.-Z., Zwiers, P. J., Hernandez Garcia, M. L., Luxen, M., van Meurs, M., Kamps, J. A. A. M., Moser, J. & Molema, G., dec.-2024, In: Journal of Leukocyte Biology. 116, 6, blz. 1479–1497 19 blz.

Onderzoeksoutput › › peer review

Sepsis induces heterogeneous transcription of coagulation- and inflammation-associated genes in renal microvasculature

Luxen, M., Zwiers, P. J., Jongman, R. M., Moser, J., Pultar, M., Skalicky, S., Diendorfer, A. B., Hackl, M., van Meurs, M. & Molema, G., mei-2024, In: Thrombosis Research. 237, blz. 112-128 17 blz.

Onderzoeksoutput › › peer review

Renal Microvascular Endothelial Heterogeneity In Sepsis: A Multiomics Approach

Luxen, M., 2023, [Groningen]: University of Groningen. 271 blz.

Onderzoeksoutput

Unique miRNome and transcriptome profiles underlie microvascular heterogeneity in mouse kidney

Luxen, M., Zwiers, P. J., Meester, F., Jongman, R. M., Kuiper, T., Moser, J., Pultar, M., Skalicky, S., Diendorfer, A. B., Hackl, M., van Meurs, M. & Molema, G., 2023, In: American journal of physiology-Renal physiology. 325, 3, blz. F299-F316

Onderzoeksoutput › › peer review

Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro

Ellermann, S. F., Jongman, R. M., Luxen, M., Kuiper, T., Plantinga, J., Moser, J., Scheeren, T. W. L., Theilmeier, G., Molema, G. & Van Meurs, M., 1-dec.-2022, In: Frontiers in Pharmacology. 13, 13 blz., 992262.

Onderzoeksoutput › › peer review

Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design

Luxen, M., van Meurs, M. & Molema, G., mei-2022, In: Frontiers in Immunology. 13, 25 blz., 867625.

Onderzoeksoutput › peer review

Pharmacological inhibition of focal adhesion kinase 1 (FAK1) and anaplastic lymphoma kinase (ALK) identified via kinome profile analysis attenuates lipopolysaccharide-induced endothelial inflammatory activation

Dayang, E.-Z., Luxen, M., Kuiper, T., Yan, R., Rangarajan, S., Meurs, M. V., Moser, J. & Molema, G., jan.-2021, In: Biomedicine & Pharmacotherapy. 133, 13 blz., 111073.

Onderzoeksoutput › › peer review

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