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Research Zernike (ZIAM) Molecular Biophysics van der Zaag group

Publications

of Pieter Jan van der Zaag

2024

van der Zaag, P. J., Keizers, B., Nijboer, T. S., & Voskuil, F. J. (2024). Image processing device and medical treatment device including the same. (Patent No. WO2024162850).
van der Zaag, P. J., Keizers, B., Nijboer, T. S., van Boven, L. M., & Kuiper, J. S. (2024). Method and device of inspecting a fluorescent image of a mammal tissue and medical treatment device. (Patent No. WO2024186210).
van der Zaag, P. (2024). NWO Physics 2024: verslag van de groepsleidersavond. Nederlands Tijdschrift voor Natuurkunde, 2024(5), 10-11.
Keizers, B., Nijboer, T. S., van der Fels, C. A. M., van den Heuvel, M. C., van Dam, G. M., Kruijff, S., de Jong, I. J., Witjes, M. J. H., Voskuil, F. J., Gorpas, D., Browne, W. R., & van der Zaag, P. J. (2025). Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW. Journal of biomedical optics, 30(S1), Article S13708. Advance online publication. https://doi.org/10.1117/1.JBO.30.S1.S13708
van der Zaag, P. J., & Coehoorn, R. (2024). The Philips NatLab years: 1964–1994. Journal of Alloys and Compounds, 994, Article 174663. https://doi.org/10.1016/j.jallcom.2024.174663

2023

Johnson, M. T., Bulut, M., van der Zaag, P. J., Macinnes, A., & Bouwman, W. (2023). Health database updating. (Patent No. US20230386625).

2022

van der Zaag, P. J., & Pedersen, J. A. (2022). Extraluminal imaging based intraluminal therapy guidance systems, devices, and methods. (Patent No. WO2022078744).
van der Zaag, P. J., Fitchorova, O., Sokolov, A., & Harris, V. G. (2022). Ferrite Films: Deposition Methods and Properties in View of Applications. In V. G. Harris (Ed.), Modern Ferrites: Basic Principles, Processing and Properties (Vol. 1, pp. 295-411). John Wiley and Sons Ltd. https://doi.org/10.1002/9781118971499.ch10
Yang, L., Rivandi, M., Franken, A., Hieltjes, M., van der Zaag, P. J., Nelep, C., Eberhardt, J., Peter, S., Niederacher, D., Fehm, T., & Neubauer, H. (2022). Implementing microwell slides for detection and isolation of single circulating tumor cells from complex cell suspensions. Cytometry. Part A, 101(12), 1057-1067. https://doi.org/10.1002/cyto.a.24660
van der Zaag, P. J. (2022). Next generation sequencing: Een revolutie in genoomanalyse voor kankerdiagnostiek en infectieziekten. Nederlands Tijdschrift voor Natuurkunde, 88(9), 16-21.
Hulsen, T., van der Zaag, P. J., & Raaijmakers, G. (2022). Variable allele frequency threshold. (Patent No. WO2022243149).

2021

Voskuil, F. J., Vonk, J., van der Vegt, B., Kruijff, S., Ntziachristos, V., van der Zaag, P. J., Witjes, M. J. H., & van Dam, G. M. (2022). Intraoperative imaging in pathology-assisted surgery. Nature biomedical engineering, 6(5), 503–514 . https://doi.org/10.1038/s41551-021-00808-8
Vulders, R. C. M., Boamfa, M. I., van der Zaag, P. J., & Asselman, M. J. A. (2021). A dynamic ferrofluid barrier for a biological sample. (Patent No. WO2021037712).
van der Zaag, P. J., Verhaegh, W. F. J., & Keupp, J. (2021). Apparatus for diagnostic image acquisition determination. (Patent No. WO2021099280).
Vulders, R. C. M., van Hoogenhuizen, R. C., van der Giessen, E., & van der Zaag, P. (2021). Clearing-induced tissue shrinkage: A novel observation of a thickness size effect. PLoS ONE, 16(12), Article e0261417. https://doi.org/10.1371/journal.pone.0261417
van der Zaag, P. J. (2021). Ferrites. In M. Pomeroy (Ed.), Encyclopedia of Materials: Technical Ceramics and Glasses (Vol. 3, pp. 217-224). Elsevier. https://doi.org/10.1016/B978-0-12-803581-8.02337-7
Noltes, M. E., van Dam, G. M., Nagengast, W. B., van der Zaag, P. J., Slart, R. H. J. A., Szymanski, W., Kruijff, S., & Dierckx, R. A. J. O. (2021). Let’s embrace optical imaging: A growing branch on the clinical molecular imaging tree. European Journal of Nuclear Medicine and Molecular Imaging, 48(13), 4120-4128. https://doi.org/10.1007/s00259-021-05476-z
van der Zaag, P. J., & Verhaegh, W. F. J. (2021). Method and apparatus for assessing patient's response to therapy. (Patent No. WO2021074091).

2020

van der Zaag, P. J., Boamfa, M. I., Asselman, M. J. A., & Vulders, R. C. M. (2020). A simple and efficient biopsy scanner with improved z-axis resolution. (Patent No. EP3748414).
Boamfa, M. I., Asselman, M. J. A., Vulders, R. C. M., Verhoef, E. I., Van Royen, M. E., & Van Der Zaag, P. J. (2020). Combined transmission, dark field and fluorescence microscopy for intact, 3D tissue analysis of biopsies. Journal of Biomedical Optics, 25(11), Article 116503. https://doi.org/10.1117/1.JBO.25.11.116503
Boamfa, M. I., van der Zaag, P. J., van Hoogenhuizen, R. C., Asselman, M. J. A., & Vulders, R. C. M. (2020). Correlated image analysis for 3d biopsy. (Patent No. WO2020182720).
Van Der Zaag, P. J. (2020). (Keynote Paper) Mono-Domain Ferrites and Their Implications. IEEE Transactions on Magnetics, 56(6), Article 9033989. https://doi.org/10.1109/TMAG.2020.2980505
Boamfa, M. I., van der Zaag, P. J., Asselman, M. J. A., Vulders, R. C. M., & van Hoogenhuizen, R. (2020). Variable incidence angle dark-field microscopy. (Patent No. EP3663812).

2019

Boamfa, M. I., van der Zaag, P. J., & Larsen, N. A. (2019). A multi-mode imager. (Patent No. WO2019096974).
van der Zaag, P. J., & Varekamp, C. (2019). Biopsy container with identifier. (Patent No. WO2019/092168).
van der Zaag, P. J., & Steffen, T. (2019). Device and method for providing information about a biopsy taking process and biopsy system. (Patent No. WO2019105866).
Boamfa, M. I., Vulders, R. C. M., & van der Zaag, P. J. (2019). Method of handling a biopsy sample. (Patent No. WO2019101657).
van der Zaag, P. J., Varekamp, C., Pedersen, J., & Hendriks, B. H. W. (2019). System for affecting a subject. (Patent No. WO2019215056).

2018

Varekamp, C., van der Zaag, P. J., & Asselman, M. J. A. (2018). Apparatus for tubulus detection from a tissue biopsy. (Patent No. WO2018041745).
van der Zaag, P. J., Vulders, R. C. M., & Clout, D. E. W. (2018). Device for processing 3d biopsy tissue. (Patent No. WO2018162640).
van der Zaag, P. J., Vulders, R. C. M., & Podenphant Jensen, M. (2018). Microfluidic device for accommodating, isolating, treating and/or processing cells having an inlet chamber with a chute structure. (Patent No. WO2018109008).
Weerts, M. J. A., Timmermans, E. C., Vossen, R. H. A. M., van Strijp, D., Van den Hout-van Vroonhoven, M. C. G. N., van Ikken, W. F. J., van der Zaag, P. J., Anvar, S. Y., Sleijfer, S., & Martens, J. W. M. (2018). Sensitive detection of mitochondrial DNA variants for analysis of mitochondrial DNA-enriched extracts from frozen tumor tissue. Scientific Reports, 8, Article 2261. https://doi.org/10.1038/s41598-018-20623-7
Marie, R., Podenphant, M., Koprowska, K., Baerlocher, L., Vulders, R. C. M., Wilding, J., Ashley, N., McGowan, S. J., van Strijp, D., van Hemert, F., Olesen, T., Agersnap, N., Bilenberg, B., Sabatel, C., Schira, J., Kristensen, A., Bodmer, W., van der Zaag, P. J., & Mir, K. U. (2018). Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device. Lab on a Chip, 18(13), 1891-1902. https://doi.org/10.1039/c8lc00169c

2017

van der Zaag, P., Hendriks, B. H. W., & Varekamp, C. (2017). Biopsy container. (Patent No. WO2017194563).
van Strijp, D., Vulders, R. C. M., Larsen, N. A., Schira, J., Baerlocher, L., van Driel, M. A., Podenphant, M., Hansen, T. S., Kristensen, A., Mir, K. U., Olesen, T., Verhaegh, W. F. J., Marie, R., & van der Zaag, P. J. (2017). Complete sequence-based pathway analysis by differential on-chip DNA and RNA extraction from a single cell. Scientific Reports, 7, Article 11030. https://doi.org/10.1038/s41598-017-10704-4
van der Zaag, P. J., Vulders, R. C. M., Clout, D. E. W., van Eemeren, J. T. W. M., & van de Stolpe, A. (2017). Device for processing of 3d biopsy tissue. (Patent No. WO2017109201).
Verschuuren, M. A., & van der Zaag, P. J. (2017). Method of creating a nano-sized recess. (Patent No. WO2017108591).
van der Zaag, P. J., Marie, R. C. W., van Strijp, D. A. M., Olesen, T., & Vulders, R. C. M. (2017). Microfluidic device possessing structures enabling differential analysis of a single cell's constituents. (Patent No. WO2017085032).

2016

van der Zaag, P. J., van der Vleuten, C. A. N. M., Hendriks, B. H. W., Lucassen, G. W., & Wijbrans, K. C. J. (2016). Device for obtaining 3d biopsy. (Patent No. WO2016075061).
van der Zaag, P. (2016). Ferrites. In S. Hashmi (Ed.), Reference Module in Materials Science and Materials Engineering Elsevier.
van der Zaag, P., & Pierik, A. (2016). Optical controlling of a chemical reaction. (Patent No. WO2016046408).
van der Zaag, P., Neijzen, J. H. M., Prins, M., Nieuwenhuis, J. H., Toon Hendrik, E., & Stroucken, L. (2016). Single cartridge for multiple detection modalities. (Patent No. WO2016162450).

2015

McGinn, S., Bauer, D., Brefort, T., Dong, L., El-Sagheer, A., Elsharawy, A., Evans, G., Falk-Sörqvist, E., Forster, M., Fredriksson, S., Freeman, P., Freitag, C., Fritzsche, J., Gibson, S., Gullberg, M., Gut, M., Heath, S., Heath-Brun, I., Heron, A. J., ... Gut, I. G. (2016). New Technologies for DNA analysis-A review of the READNA Project. New Biotechnology, 33(3), 311-330. https://doi.org/10.1016/j.nbt.2015.10.003
Eshoo, M. W., Hang, A., Chou, D., Smith, H., Picuri, J., Rosenzweig, C. N., Broomall, S. M., Carcel, P., Crowder, C., Chiesl, T., Motley, S. T., Pierik, A., Feitsma, H., Dobbelaer, I., Meijring, B., van Zelst, M., Bruyninckx, M., Kragt, R., Loring, T. A. J., ... van der Zaag, P. (2015). Automated Microfluidic Sample to Sequence System for Pathogen Detection. Poster session presented at Advances in Genome Biology and Technology Conference, United States.
Schleipen, J. J. H. B., Wimberger-Friedl, R., van der Zaag, P. J., Urbach, H. P., & Sarkar, M. (2015). Biosensor comprising waveguide. (Patent No. WO2015082247).
van Eemeren, J. T. W. M., Dobbelaer-Bosboom, I. J. M., & van der Zaag, P. J. (2015). Microfluidic device with valve. (Patent No. WO2015022176).
van der Zaag, P. J., & Pierik, A. (2015). Optical controlling of a chemical reaction. (Patent No. WO2015078755).

2014

van de Stolpe, A., Feitsma, H. M., van der Zaag, P. J., Wimberger-Friedl, R., den Toonder, J. M. J., Pierik, A., & van Hemert, F. (2014). Processing of nucleotide sequences. (Patent No. WO2014122548).
Sarkar, M., Wachters, A. J. H., Urbach, H. P., Schleipen, J. J. H. B., van der Zaag, P. J., & Wimberger-Friedl, R. (2014). Waveguide structures for efficient evanescent field coupling to zero mode waveguides. Journal of the european optical society-Rapid publications, 9, Article 14019. https://doi.org/10.2971/jeos.2014.14019

2013

van der Zaag, P. J., Coehoorn, R., & van Delft, F. C. M. J. (2013). Apparatus for the processing of single molecules. (Patent No. WO2013046116).
Wimberger-Friedl, R., Lub, J., & van der Zaag, P. J. (2013). Dna sequencing with reagent recycling on wiregrid. (Patent No. WO2013105025).
Ovsyanko, M. M., van der Zaag, P. J., Feitsma, H. M., Wimberger-Friedl, R., Löring, T. A. J., & van Zelst, M. J. (2013). Magnetically assisted processing of a medium. (Patent No. WO2013171600).
van der Zaag, P. J., Peeters, E., Koole, R., & van Delft, F. C. M. J. (2013). Manufacturing method of an apparatus for the processing of single molecules. (Patent No. WO2013140316).

2012

Craus, C. B., den Toonder, J. M. J., Penterman, R., & van der Zaag, P. J. (2012). Device for fragmenting molecules in a sample by ultrasound. (Patent No. WO2012168853).
Servoli, E., Feitsma, H., Kaptheijns, B., van der Zaag, P. J., & Wimberger-Friedl, R. (2012). Improving DNA capture on microarrays by integrated repeated denaturing. Lab on a Chip, 12(23), 4992-4999. https://doi.org/10.1039/c2lc40691h
van der Zaag, P. J., Dimitrova, N., van de Stolpe, A., & van Houten, H. (2012). In vitro diagnostic testing including automated brokering of royalty payments for proprietary tests. (Patent No. WO2012059839).
Feitsma, H. M., Overdijk, M. J., van de Stolpe, A., & van der Zaag, P. J. (2012). Method for amplifying nucleic acids. (Patent No. WO2012029037).
Wimberger-Friedl, R., van der Zaag, P. J., & Servoli, E. (2012). Method for performing molecular reactions by using immiscible intermediate fluids. (Patent No. WO2012127413).
van der Zaag, P. J., Amberg, R., Verhaegh, W. F. J., Beyerlein, P., & Boettcher, R. (2012). Providing nucleotide sequence data. (Patent No. WO2012168803).
Böttcher, R., Amberg, R., Ruzius, F. P., Guryev, V., Verhaegh, W. F. J., Beyerlein, P., & van der Zaag, P. J. (2012). Using a priori knowledge to align sequencing reads to their exact genomic position. Nucleic Acids Research, 40(16), Article e125. https://doi.org/10.1093/nar/gks393

2011

den Toonder, J. M. J., van der Zaag, P. J., & Chao, H. C. (2011). Device and method for transporting magnetic or magnetisable beads. (Patent No. WO2011030272).
van der Zaag, P. J., Feitsma, H. M., den Toonder, J. M. J., & Wimberger-Friedl, R. (2011). Devices and methods for microarray selection. (Patent No. WO2011027268).
Mertes, F., ElSharawy, A., Sauer, S., van Helvoort, J. M. L. M., van der Zaag, P. J., Franke, A., Nilsson, M., Lehrach, H., & Brookes, A. J. (2011). Targeted enrichment of genomic DNA regions for next-generation sequencing. Briefings in Functional Genomics, 10(6), 374-386. https://doi.org/10.1093/bfgp/elr033

2010

Mokry, M., Feitsma, H., Nijman, I. J., de Bruijn, E., van der Zaag, P. J., Guryev, V., & Cuppen, E. (2010). Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries. Nucleic Acids Research, 38(10), e116. https://doi.org/10.1093/nar/gkq072
van der Zaag, P. J., & Borchers, J. A. (2010). Antiferromagnetic-Ferromagnetic Oxide Multilayers: Fe3O4-Based Systems as a Model. In L. Duò, M. Finazzi, & F. Ciccacci (Eds.), Magnetic Properties of Antiferromagnetic Oxide Materials: Surfaces, Interfaces, and Thin Films (pp. 239-300). Wiley. https://doi.org/10.1002/9783527630370.ch7
van de Stolpe, A., den Toonder, J. M. J., & van der Zaag, P. J. (2010). Genomic selection and sequencing using encoded microcarriers. (Patent No. WO2010097775).
Prins, M., van der Zaag, P. J., & den Dulk, R. C. (2010). Microfluidic device. (Patent No. WO2010041174).
van der Zaag, P. J., van de Stolpe, A., McCoo, E., & van Wanrooij, E. J. A. (2010). Nanopore device and a method for nucleic acid analysis. (Patent No. WO2010007537).

2009

Narayanaswamy, A., Feiner, L. F., Meijerink, A., & van der Zaag, P. J. (2009). The Effect of Temperature and Dot Size on the Spectral Properties of Colloidal InP/ZnS Core-Shell Quantum Dots. Acs Nano, 3(9), 2539-2546. https://doi.org/10.1021/nn9004507

2008

van der Zaag, P. J., French, I., & Young, N. D. (2008). A photodiode for detection within molecular diagnostics. (Patent No. WO2008012705).
Wimberger-Friedl, R., Young, N. D., & van der Zaag, P. J. (2008). Biosensor with evanescent waveguide and integrated sensor. (Patent No. WO2008096296).
Narayanaswamy, A., Feiner, L. F., & van der Zaag, P. J. (2008). Temperature dependence of the photoluminescence of InP/ZnS quantum dots. Journal of Physical Chemistry C, 112(17), 6775-6780. https://doi.org/10.1021/jp800339m

2007

van der Zaag, P. J., Young, N. D., & Stapert, H. R. (2007). Integrated device having an array of photodetectors and an array of sample sites. (Patent No. WO2007110810).
Ijiri, Y., Schulthess, T. C., Borchers, J. A., van der Zaag, P. J., & Erwin, R. W. (2007). Link between perpendicular coupling and exchange biasing in Fe3O4/CoOMultilayers. Physical Review Letters, 99(14), Article 147201. https://doi.org/10.1103/PhysRevLett.99.147201
van der Zaag, P. J., Bakkers, E. P. A. M., & van der Mark, M. B. (2007). Luminescent particle and method of detecting a biological entity using a luminescent particle. (Patent No. WO2007060591).

2004

van der Zaag, P. J., Young, N. D., & French, I. D. (2004). Tft electronic devices and their manufacture. (Patent No. WO2004006339).

2003

Yoon, S. Y., Young, N., van der Zaag, P. J., & McCulloch, D. (2003). High-performance poly-Si TFTs made by Ni-mediated crystallization through low-shot laser annealing. IEEE Electron Device Letters, 24(1), 22-24. https://doi.org/10.1109/LED.2002.807019
van der Zaag, P. J., Edwards, M. J., & Lenssen, K.-M. H. (2003). In-pixel memory for display devices. (Patent No. WO03081599).
van der Zaag, P. J., Yoon, S. Y., & Young, N. D. (2003). Manufacture of active matrix display devices. (Patent No. WO03098671).
van der Zaag, P. J., Edwards, M. J., & Lenssen, K.-M. H. (2003). Memories and memory circuits. (Patent No. WO03096351).
van der Zaag, P. J., Edwards, M. J., & Lenssen, K.-M. H. (2003). Mram in-pixel memory for display devices. (Patent No. WO03107316).

2002

French, I. D., & van der Zaag, P. J. (2002). Active matrix liquid crystal displays and methods of manufacturing such. (Patent No. WO0259690).
Deane, S. C., van der Zaag, P. J., & Battersby, S. J. (2002). An electronic device including a thin film transistor. (Patent No. WO0291475).
van der Zaag, P. J., Verheijen, M. A., Yoon, S. Y., & Young, N. D. (2002). Explanation for the leakage current in polycrystalline-silicon thin-film transistors made by Ni-silicide mediated crystallization. Applied Physics Letters, 81(18), 3404-3406. https://doi.org/10.1063/1.1517406
French, I. D., van der Zaag, P. J., & de Kubber, D. L. (2002). Method of improving the conductivity of transparent conductor lines. (Patent No. WO0263386).
French, I. D., & van der Zaag, P. J. (2002). Method of increasing the conductivity of a transparent conductive layer. (Patent No. WO0244805).
van der Zaag, P. J., Deane, S. C., & Battersby, S. J. (2002). Method of manufacturing a thin film transistor. (Patent No. WO0291454).
Chapman, J. A., van der Zaag, P. J., Deane, S. C., & French, I. D. (2002). Pixellated devices such as active matrix liquid crystal displays. (Patent No. WO0244804).

2001

van der Zaag, P. J. (2001). Ferrites. In K. H. J. Buschow, R. W. Cahn, M. C. Flemings, B. Ilschner, E. J. Kramer, S. Mahajan, & P. Veyssière (Eds.), Encyclopedia of Materials: Science and Technology (2 ed., pp. 3033-3037). Elsevier. https://doi.org/10.1016/B0-08-043152-6/00542-8
van der Zaag, P. J., Lefeuvre, S., & Bisschops, T. (2001). Hysteresis in the hopping current of secondary electrons over MgO: the role of CO2 and surface cleanness. Vacuum, 60(1-2), 241-245. https://doi.org/10.1016/S0042-207X(00)00390-0
Wolf, R. M., & van der Zaag, P. J. (2001). Magnetic component. (Patent No. WO0161715).

2000

van der Zaag, P. J., Dekker, R., & Dolmans, W. M. C. (2000). A semiconductor device with an operating frequency larger than 50mhz comprising a body composed of a soft ferrite material. (Patent No. WO0065655).
van der Zaag, P. J., Ijiri, Y., Borchers, J. A., Feiner, L. F., Wolf, R. M., Gaines, J. M., Erwin, R. W., & Verheijen, M. A. (2000). Difference between blocking and Néel temperatures in the exchange biased Fe3O4/CoO system. Physical Review Letters, 84(26), 6102-6105. https://doi.org/10.1103/PhysRevLett.84.6102
van der Zaag, P. J., Bloemen, P. J. H., Gaines, J. M., Wolf, R. M., van der Heijden, P. A. A., van de Veerdonk, R. J. M., & de Jonge, W. J. M. (2000). On the construction of an Fe3O4-based all-oxide spin valve. Journal of Magnetism and Magnetic Materials, 211(1-3), 301-308. https://doi.org/10.1016/S0304-8853(99)00751-9
Doss Desouza, A. F. C., Smidt, P. J. M., & van der Zaag, P. J. (2000). Power cord provided with a power cord transformer. (Patent No. WO0005786).
van der Zaag, PJ., Feiner, LF., Wolf, RM., Borchers, JA., Ijiri, YY., & Erwin, RW. (2000). The blocking and Neel temperature in exchange-biased Fe3O4/CoO multilayers. Physica B, 276(2nd European Conference on Neutron Scattering (ECNS 99)), 638-639. https://doi.org/10.1016/S0921-4526(99)01392-7

1999

Fontijn, WFJ., van der Zaag, PJ., Feiner, LF., Metselaar, R., & Devillers, MAC. (1999). A consistent interpretation of the magneto-optical spectra of spinel type ferrites (invited). Journal of Applied Physics, 85(8), 5100-5105. https://doi.org/10.1063/1.369091
Hibma, T., Voogt, F. C., Niesen, L., van der Heijden, P. A. A., de Jonge, W. J. M., Donkers, J. J. T. M., & van der Zaag, P. J. (1999). Anti-phase domains and magnetism in epitaxial magnetite layers. Journal of Applied Physics, 85(8), 5291 - 5293. https://doi.org/10.1063/1.369857
Aarts, J., Abu Shiekah, I., & van der Zaag, PJ. (1999). Domain structure in polycrystalline MnZn ferrite imaged by magnetic force microscopy. Journal of Applied Physics, 85(10), 7302-7309. https://doi.org/10.1063/1.369353
van der Zaag, P., & Berkowitz, A. (1999). John Paul Jakubovics - Obituary. Physics today, 52(1), 83. https://doi.org/10.1063/1.882590
Last modified:09 June 2023 8.36 p.m.