Publicaties 2014

Hieronder vindt u de publicaties van de basiseenheid Farmaceutische Biologie in 2014. Indien u op een titel klikt, dan wordt u (indien mogelijk) automatisch naar de publicatie doorgelinked.

Azijli, Kaamar; van Roosmalen, Ingrid A. M.; Smit, Jorn; Pillai, Saravanan; Fukushima, Masakazu; de Jong, Steven; Peters, Godefridus J.; Bijnsdorp, Irene V.; Kruyt, Frank A. E. The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells. CANCER CHEMOTHERAPY AND PHARMACOLOGY, Vol. 73(6):1273-1283.

Baas, B-J., Zandvoort, E., Wasiel, A.A, Poelarends, G.J.. Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase. In, FEBS Open Bio,4, 651-658.

Boersma, Ykelien L; Newman, Janet; Adams, Timothy E; Cowieson, Nathan; Krippner, Guy; Bozaoglu, Kiymet; Peat, Thomas S The structure of vanin 1 : a key enzyme linking metabolic disease and inflammation. Acta Crystallographica Section D Biological Crystallography, Vol. 70, No. Pt 12:3320-3329.

Bosman, M.C., Reis, C.R., Schuringa, J.J., Vellenga, E. and Quax, W.J. Decreased Affinity of Recombinant Human Tumor Necrosis Factor-related Apoptosis-inducing Ligand (rhTRAIL) D269H/E195R to Osteoprotegerin (OPG) Overcomes TRAIL Resistance Mediated by the Bone Microenvironment. J.Biol.Chem. 289 (2)1071-1078.

Bosman, Matthieu Cornelis Johannes; Schepers, Hein; Jaques, Jennifer; Vos, Annet; Quax, Wim Johannes; Schuringa, Jan Jacob; Vellenga, Edo The TAK1-NF-κB axis as therapeutic target for AML. Blood;124(20):3130-40.

Elfahmi, Woerdenbag, H.J. and Kayser, O. Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use. Journal of Herbal Medicine. 4, 51-73

Kiuchi, Tai; Ortiz-Zapater, Elena; Monypenny, James; Matthews, Daniel R; Nguyen, Lan K; Barbeau, Jody; Coban, Oana; Lawler, Katherine; Burford, Brian; Rolfe, Daniel J; de Rinaldis, Emanuele; Dafou, Dimitra; Simpson, Michael A; Woodman, Natalie; Pinder, Sarah; Gillett, Cheryl E; Devauges, Viviane; Poland, Simon P; Fruhwirth, Gilbert; Marra, Pierfrancesco; Boersma, Ykelien L; Plückthun, Andreas; Gullick, William J; Yarden, Yosef; Santis, George; Winn, Martyn; Kholodenko, Boris N; Martin-Fernandez, Marisa L; Parker, Peter; Tutt, Andrew; Ameer-Beg, Simon M; Ng, Tony The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility. Sci Signal.;7(339):ra78.

Koch, G., Nadal-Jimenez P., Reis C.R., Muntendam R., Bokhove, M., Melillo, E., Dijkstra, B.W., Cool, R.H., Quax, W.J. Reducing virulence of the human pathogen Burkholderia by altering the substrate specificity of the quorum-quenching acylase PvdQ. PNAS 111(4):1568-1573.

Koch G., Jimenez, P.N., Cool, R.H., Quax, W.J. Deinococcus radiodurans can interfere with quorum sensing by expressing an AHL-acylase and an AHL-lactonase. FEMS Microbiol Lett.  Vol 356(1):62-70.

Kusari, P., Kusari, S., Lamshoft, M., Sezgin, S., Spiteller, M.. Kayser, O. Quorum quenching is an antivirulence strategy employed by endophytic bacteria. Appl.Microbiol.Biotechnol 98, 7173-7183

Lambrechts, R.A., Srinivasan, B., Geertsema, E.M., Poelarends, G.J., Sibon, O.C.M., de Villiers, M. Synthesis and characterization of 4-thiobutyl triphenylphosphonium-pantetheine, a pantetheine derivative. American Chemical Science Journal 4(5), 676-686.

Nadal-Jimenez, P., Koch, G., Reis, C.R., Muntendam, R., Raj, H., Jeronimus-Stratingh, C.M., Cool, R.H., Quax, W.J. PvdP is a tyrosinase that drives maturation of the pyoverdine chromophore in Pseudomonas aeruginosa . J. Bacteriol.,Vol 196(14):2681-2690.

Ourailidou, M.E., van der Meer, J.Y., Baas, B.J., Jeronimus-Stratingh, M., Gottumukkala, A.L., Poelarends, G.J., Minnaard, A.J., Dekker, F.J. Aqueous oxidative Heck reaction as a protein labeling strategy. ChemBioChem 15(2):209-212.

Rozeboom, H.J., Godinho, L.F., Nardini , M., Quax, W,J., Dijkstra, B.W. Crystal structures of two Bacillus carboxylesterases with different enantioselectivities. Biochim Biophys Acta 844(3):567-575.

van Roosmalen, Ingrid A; Rodrigues Dos Reis, Carlos; Setroikromo, Rita; Yuvaraj, Saravanan; Joseph, Justin V; Tepper, Pieter G; Kruyt, Frank A; Quax, Wim J The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma. SpringerPlus, Vol. 3(1):495.

van Roosmalen, Ingrid A.M.; Quax, Wim J.; Kruyt, Frank A.E. Two death-inducing human TRAIL receptors to target in cancer : Similar or distinct regulation and function?. Biochemical Pharmacology 91(4):447-456.

Yu, Rui; Albarenque, Stella Maris; Cool, Robbert H; Quax, Wim J; Mohr, Andrea; Zwacka, Ralf M. DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer. Cancer biology & therapy, Vol. 15(12):1658-1666.

Hoofdstuk in boek

Insanu, Muhamad; Setoikromo, Rita; Tepper, Pieter; Jeronimus-Stratingh, Hjalmar Permentier; van der Linde, Piet; Brooker, John; Kayser, Oliver; Quax, Wim J. Validation of detoxification process for Jatropha curcas L. kernel meal for use as animal feed. Rational Use of Jatropha curcas L. in Food and Medicine. 2014. p. 100.

Insanu, Muhamad; Tepper, Pieter; Jeronimus, Margot; Quax, Wim; Kayser, Oliver Development of tandem mass spectrometry for dehydroxy phorbol esters and phorbol myristate acetate analysis. Rational Use of Jatropha curcas L. in Food and Medicine. 2014. p. 55.

Geertsema, E.M., Poelarends, G.J. Enzymatic carbon-carbon bond-forming Michael-type additions. In K. Faber, W.-D. Fessner, and N. Turner (eds.), Science of Synthesis: Biocatalysis in Organic Synthesis, 1 ed, volume 2, 313-334.Thieme

Koch, G., Nadal-Jimenez, P, Cool, R.H., Quax ,W.J. Assessing Pseudomonas Virulence with Nonmammalian Host: Galleria mellonella. In: Methods Mol Biol. 2014;1149:681-6888. doi: 10.1007/978-1-4939-0473-0_52.

Proefschriften

Insanu M. Rational Use of Jatropha curcas L. in Food and Medicine: From Toxicity Problems to Safe Applications.

24 oktober 2014

ISBN: 978-90-367-7315-7 (gedrukte versie)

ISBN: 978-90-367-7314-0 (electronische versie).

van Roosmalen, I.A.M. TRAIL receptor-targeted therapy. Strategies to enhance DR4- and DR5-induced apoptosis.

19 december 2014

ISBN: 978-90-367-7489-5 (gedrukte versie)

ISBN: 978-90-367-7587-1 (electronische versie).

Baas, J.B. Exploring Chemical Versatility within the Tautomerase Superfamily. Catalytic Promiscuity and the Emergence of New Enzymes.

22 december 2014

ISBN: 978-94-6295-053-5 (gedrukte versie)

Patenten

TNF FAMILY LIGAND VARIANTS

QUAX WILHELMUS JOHANNES; TUR VICENTE R; SERRANO LUIS; VAN DER SLOOT ALBERT MARTINUS; COOL ROBBERT H; VAN ASSEN AART H G.

Publicatiedatum: 2014-04-03

Patentnummer: US201113997311 20111223

NOVEL METHANOL DEHYDROGENASE ENZYMES FROM BACILLUS

BRAUTASET TRYGVE; HEGGESET TONJE MARITA BJERKAN; KROG ANNE; QUAX WILHELMUS JOHANNES; SIBBALD MARK JAN JACOBUS BERNHARD; VORHOLT JULIA; MULLER JONAS; KIEFER PATRICK; POTTHOFF EVA; WENDISCH VOLKER F; LESSMEIER LENNART; HEUX STEPHANIE; PORTAlS JEAN-CHARLES

Publicatiedatum:2014-12-03

Patentnummer: EP20130701767 20130125