Publications 2009

Below you will find the publications of the department of Pharmaceutical Biology for 2009. The title of the publication links automatically to the PDF-file (when available). 

Wu, B., Szymanski, W., Wietzes, P., de Wildeman, S., Poelarends, G.J., Feringa, B.L., and Janssen, D.B. Enzymatic synthesis of enantiopure α - and β-amino acids by phenylalanine aminomutase-catalyzed amination of cinnamic acid derivatives. ChemBioChem 10(2):338-44.

Dubois, J.Y., Kouwen, T.R., Schurich, A.K., Reis, C.R., Ensing, H.T., Trip, E.N., Zweers, J.C., van Dijl, J.M. Immunity to the bacteriocin sublancin 168 Is determined by the SunI (YolF) protein of Bacillus subtilis. Antimicrob. Agents. Chemother. 53(2):651-61.

Reis, C.R., van der Sloot, A.M., Szegezdi, E., Natoni, A., Tur, V., Cool, R.H., Samali, A., Serrano, L., Quax, W.J. Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors (dagger). Biochemistry 48(10):2180-91.

Duiker, E.W., de Vries, E.G., Mahalingam, D., Meersma, G.J., Boersma-van Ek, W., Hollema, H., Lub-de Hooge, M.N., van Dam, G.M., Cool, R.H., Quax, W.J., Samali, A., van der Zee, A.G., de Jong, S. Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model. Clin. Cancer. Res.15(6):2048-57.

Krzeslak, J., Braun, P., Voulhoux, R., Cool, R.H., Quax, W.J. Heterologous production of Escherichia coli penicillin G acylase in Pseudomonas aeruginosa. J. Biotechnol. 142(3-4):250-8.

Limsuwan, S., Trip, E.N., Kouwen, T.R., Piersma, S., Hiranrat, A., Mahabusarakam, W., Voravuthikunchai, S.P., van Dijl, J.M., Kayser, O. Rhodomyrtone: a new candidate as natural antibacterial drug from Rhodomyrtus tomentosa. Phytomedicine16(6-7):645-51.

Puthan Veetil, V.,  Raj, H., Quax, W.J., Janssen, D. B., Poelarends, G.J. Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1. FEBS J. 276(11):2994-3007.

Muntendam, R., Melillo, E., Ryden, A., Kayser, O. Perspectives and limits of engineering the isoprenoid metabolism in heterologous hosts. Appl Microbiol Biotechnol. 84(6):1003-1019.

Raj, H., Weiner, B., Puthan Veetil, V., Reis, C.R., Quax, W.J., Janssen, D.B., Feringa, B.L., Poelarends, G.J. Alteration of the Diastereoselectivity of 3-Methylaspartate Ammonia Lyase by Using Structure-Based Mutagenesis. Chembiochem. 10(13):2236-2245.

Staniek, A., Woerdenbag, H.J., Kayser, O. Taxomyces andreanae: A Presumed Paclitaxel Producer Demystified? Planta Med. 75(15):1561-1566.

Griewel, A., Kayser, O., Schlosser, J., Rarey, M. Conformational Sampling for Large-Scale Virtual Screening: Accuracy versus Ensemble Size. J. Chem. Inf. Model. 49(10):2303-2311.

Nadal Jimenez P., Koch, G., Papaioannou,E., Wahjudi, M., Krzeslak, J., Coenye, T., Cool, R.H., Quax, W.J. The role of PvdQ in Pseudomonas aeruginosa virulence under iron limiting conditions. Microbiology 2009 Sep 24. Epub ahead of print.

Papaioannou, E., Wahjudi, M.,  Nadal Jimenez, P, Koch, G., Setroikromo, R., Quax, W.J. Quorum quenching acylase reduces the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model. Antimicrob. Agents Chemother. 53(11) p 4891-4897.

Kouwen , T.R., Nielsen,  A.K., Denham, E.L., Dubois, J.Y., Dorenbos, R., Rasmussen, M.D., Quax, W.J., Freudl, R., van Dijl, J.M. Contributions of the pre- end pro-regions of Staphylococcus hyicus lipase to secretion of a heterologous protein by Bacillus subtilis. Appl Environ Microbiol . Nov 30. Epub ahead of print.

Staniek, A., Muntendam, R., Woerdenbag, H.J., Kayser, O. Essential oil constituents derived from different organs of a relictual conifer Wollemia nobilis. Biochemical Systematics and Ecology, DOI 10.1016/j.bse.2009.12.022 A ccepted for publication December 24, 2009.

Staniek, A., Woerdenbag, H.J., Kayser, O. Screening the endophytic flora of Wollemia nobilis for alternative paclitaxel sources. Journal of Plant Interactions. A ccepted for publication December 31, 2009.

Bokhove, M., Nadal Jimenez, P., Quax, W.J., Dijkstra, B.W. The quorum quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket. Proc Natl Acad Sci U S A.  doi/10.1073/pnas.0911839107. Epub December 22, 2009.

Azizi, M., Davareenejad, G., Bos, R., Woerdenbag ,H.J., Kayser, O. Essential oil content and constituents of black zira (Bunium persicum [Boiss.] B. Fedtsch.) from Iran during field cultivation (domestication). Journal of Essential Oil Research; 21: 78-82, 193-194.

Aslan, S., Kartal, M., Kurucu, S., Kuiper, J.M., Kruizinga, W.H., Bos, R., Woerdenbag, H.J., Kayser, O. Composition of the essential oil from roots and rhizomes of Valeriana phu L. growing wild in Turkey. Journal of Essential Oil Research; 21: 437-440.

Özbay, Ö., Aslan, S., Kartal, M., Kurucu, S., Bos, R., Woerdenbag, H.J., Kayser, O. Preliminary examination of the composition of the essential oil from roots and rhizomes of Valeriana alpestris Stev. growing in Turkey. Journal of Essential Oil Research; 21: 555-557.

Lemke, A., Petri, B, Kiderlen, A.F., Kayser, O. Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebae. Nanomedicine: Nanotechnology, Biology, and Medicine (in press).

Chapter in book:

Poelarends, G.J., and Whitman, C.P. (2008) Mechanistic and structural studies of microbial dehalogenases: How Nature cleaves a carbon-halogen bond. In L.N. Mander and H.-W. Liu (eds.), Comprehensive Natural Products II: Chemistry and Biology (in press). Elsevier, Oxford, UK.

Cool, R.H., Reis, C.R., Quax, W.J. Receptor-Specific Variants of Cytokine TRAIL with Improved Apoptotic Characteristics in “Proteins Killing Tumour Cells ”, Research-Signpost Series on Cell Death and Disease (Editors Backendorf  - Noteborn – Tavassoli). ISBN: 978-81-7895-405-9

Thesis/Dissertation:

Krzeslak, J.K. Pseudomonas as a microbial enzyme factory. The source of industrially potent enzymes and the host for heterologous enzyme production. April 17, 2009.

ISBN printed version: 978-90-367-3783-8.

ISBN digital version:978-90-367-3784-5.

Patents:

Rodrigues dos Reis, C. R., Quax, W. J., Samali, A, Szegezdi, E., Natoni, A., Cool, R. H., van der Sloot, A. M., Serrano, L., Tur, V.Improved Cytokine Design. International Publication Number and Date: WO2009066174 (A1), 2009-05-28.

Samali, A., Szegezdi, E., Mahalingam, D., Duiker, E.W., de Vries, E.G.E, de Jong, S., Rodrigues dos Reis, C.R., de Ruijter, M., Cool, R.H., Quax, W.J. Trail variants for treating cancer. International Publication Number and Date: WO2009077857 (A2), 2009-06-25.