2015

Articles:

Bidan C. M., Veldsink A. C., Meurs H., Gosens R. Airway and Extracellular Matrix Mechanics in COPD. 2015 Dec 2 In: Front Physiol. 6, 346.

Brandsma C.-A., van den Berge, M., Postma, D. S., Jonker, M. R., Brouwer, S., Pare, P. D., Sin, D. D., Bosse, Y., Laviolette, M., Karjalainen, J., Fehrmann, R. S. N., Nickle, D. C., Hao, K., Spanjer, A. I. R., Timens, W.& Franke, L. A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD. Jan-2015 In : Thorax.70, 1, p. 21-3212 p.

Cernecka H., Kersten, K., Maarsingh, H., Elzinga, C. R., de Jong, I. J., Korstanje, C., Michel, M. C. & Schmidt, M. β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase. Jul-2015 In : Naunyn-Schmiedebergs Archives of Pharmacology. 388, 7, p. 749-759 11 p.

Dekkers B. G. J., Naeimi, S., Bos, I. S. T., Menzen, M. H., Halayko, A. J., Sadeghi Hashjin, G., Meurs, H. L-Thyroxine promotes a proliferative airway smooth muscle phenotype in the presence of TGF-β1. In: American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol. 308, No. 3, 01.02.2015, p. L301-L306.

Gosens R. & Grainge, C. Bronchoconstriction and airway biology: potential impact and therapeutic opportunities. Mar-2015 In : Chest. 147, 3, p. 798-803 6 p.

Han B., Poppinga, W. J., Schmidt, M. Scaffolding during the cell cycle by A-kinase anchoring proteins. 2015 Dec. In: Pflügers Archiv: European Journal of Physiology, 467(12):2401-11.

Jansen S. R., Holman, R., Hedemann, I., Frankes, E., Elzinga, C. R. S., Timens, W., Gosens, R., de Bont, E. S. & Schmidt, M. Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. Jan-2015 In : Journal of cellular and molecular medicine. 19, 1, p. 210-226 17 p.

Kistemaker L. E. M., Slebos, D-J., Meurs, H., Kerstjens, H. A. M, Gosens, R. Anti-inflammatory effects of targeted lung denervation in patients with COPD. In: European Respiratory Journal, Vol. 46, No. 3, 04.09.2015.

Kistemaker L. E. M., Hiemstra, P. S., Bos, I. S. T., Bouwman, S., van den Berge, M., Hylkema, M. N., Meurs, H., Kerstjens, H. A. M., Gosens, R. Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells. In: Thorax, Vol. 70, No. 7, 07.2015, p. 668-676.

Kistemaker L. E. M., van Os, R.P., Dethmers-Ausema, A., Bos, I.S.T., Hylkema, Machteld N., van den Berge, M., Hiemstra, P. S., Wess, J., Meurs, H., Kerstjens, H. A. M.; Gosens, R. Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice. In: American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol. 308, No. 1, 01.01.2015, p. L96-L103.

Kistemaker L. E. M. & Gosens, R. Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling. Mar-2015 In : Trends in Pharmacological Sciences. 36, 3, p. 164-171 8 p.

Kumawat K., Gosens, R. WNT-5A: signaling and functions in health and disease. 2015 In : Cellular and Molecular Life Sciences. 72.

Meijering R. A. M., Wiersma, M., van Marion, D. M. S., Zhang, D., Hoogstra-Berends, F., Dijkhuis, A-J., Schmidt, M., Wieland, T., Kampinga, H. H., Henning, R. H. & Brundel, B. J. J. M. RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response. 21-Jul-2015 In : PLoS ONE. 10, 7, p. e0133553

Munoz-Llancao P., Henriquez, D. R., Wilson, C., Bodaleo, F., Boddeke, E.W., Lezoualc'h, F., Schmidt, M. & Gonzalez-Billault, C.(2015). Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B. 12-Aug-2015 In : The Journal of Neuroscience, 35 (32), 11315-11329. 10.1523/JNEUROSCI.3645-14.2015

Poppinga W. J., Heijink, I. H., Holtzer, L. J., Skroblin, P., Klussmann, E., Halayko, A. J., Timens, W., Maarsingh, H. & Schmidt, M. A-kinase anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle. 15-Apr-2015 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 308, 8, p. L766-L775 10 p.

Wagenaar G. T. M., Hiemstra, P.S., Gosens, R. Therapeutic potential of soluble guanylate cyclase modulators in neonatal chronic lung disease. 2015 In : American Journal of Physiology - Lung Cellular and Molecular Physiology.p. ajplung.00333.2015

Chapter in Book:

Groothuis G., Casini, A., Meurs, H., Olinga, P. Translational research in pharmacology and toxicology using precision-cut tissue slices. Human-based Systems for Translational Research. ed. / R. Coleman. Cambridge : RSC publishing, 2015. p. 38-65.

Dissertations:

Kistemaker L.E.M., Acetylcholine beyond bronchoconstriction: A regulator of inflammation and remodeling. 2015, p. 1-220. Promotores: Gosens R., Meurs H., Kerstjens H.A.M.

Kumawat K., WNT signaling in airway remodeling in asthma. Novel roles for WNT-5A in airway smooth muscle. 2015, p. 1-272. Promotores: Gosens R., Schmidt M.

Muñoz Llancao P.A., Role of EPAC in axon determination. 2015, p. 1-382. Promotores: Boddeke H.W.G.M., Schmidt M., Gonzalez-Billault C.