2012

Publications:

Cernecka H, Ochodnicky P, Lamers WH, Michel MC. Specificity evaluation of antibodies against human beta3-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol 2012;385:875-882.

Cernecka H, Veizerova L, Mensikova L, Svetlik J, Krenek P. Selective inhibitory action of Biginelli-type dihydropyrimidines on depolarization-induced arterial smooth muscle contraction. J Pharm Pharmacol 2012;64:735-741.

Dekkers BG , Pehlic A, Mariani R, Bos IS, Meurs H, Zaagsma J. Glucocorticosteroids and beta2-Adrenoceptor Agonists Synergize to Inhibit Airway Smooth Muscle Remodeling. J Pharmacol Exp Ther 2012;342:780-787.

Dekkers BG, Bos IS, Zaagsma J, Meurs H. Functional consequences of human airway smooth muscle phenotype plasticity. Br J Pharmacol 2012;166:359-367.

Gechev TS, Hille J. Molecular basis of plant stress. Cell Mol Life Sci 2012;69:3161-3163.

Grando SA, Kawashima K, Kirkpatrick CJ, Meurs H, Wessler I. The non-neuronal cholinergic system: basic science, therapeutic implications and new perspectives. Life Sci 2012;91:969-972.

Hendrawati O, Hille J, Woerdenbag HJ, Quax WJ, Kayser O. In vitro regeneration of wild chervil (Anthriscus sylvestris L.). In Vitro Cell Dev Biol Plant 2012;48:355-361.

Jankyova S, Kmecova J, Cernecka H, Mesarosova L, Musil P, Brnoliakova Z, Kyselovic J, Babal P, Klimas J. Glucose and blood pressure lowering effects of Pycnogenol(R) are inefficient to prevent prolongation of QT interval in experimental diabetic cardiomyopathy. Pathol Res Pract 2012;208:452-457.

Kistemaker LE, Oenema TA, Meurs H, Gosens R. Regulation of airway inflammation and remodeling by muscarinic receptors: Perspectives on anticholinergic therapy in asthma and COPD. Life Sci 2012.

Kolahian S, Gosens R. Cholinergic regulation of airway inflammation and remodelling. J Allergy (Cairo) 2012;2012:681258.

Li X, Gao M, Han X, Tao S, Zheng D, Cheng Y, Yu R, Han G, Schmidt M, Han L. Disruption of the phospholipase D gene attenuates the virulence of Aspergillus fumigatus. Infect Immun 2012;80:429-440.

Mehterov N, Balazadeh S, Hille J, Toneva V, Mueller-Roeber B, Gechev T. Oxidative stress provokes distinct transcriptional responses in the stress-tolerant atr7 and stress-sensitive loh2 Arabidopsis thaliana mutants as revealed by multi-parallel quantitative real-time PCR analysis of ROS marker and antioxidant genes. Plant Physiol Biochem 2012;59:20-29.

Oenema TA, Smit M, Smedinga L, Racke K, Halayko AJ, Meurs H, Gosens R. Muscarinic receptor stimulation augments TGF-beta1-induced contractile protein expression by airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2012;303:L589-97.

Oldenburger A, Maarsingh H, Schmidt M. Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung. Pharmaceuticals 2012;5 (12):1291-1331.

Oldenburger A, Roscioni SS, Jansen E, Menzen MH, Halayko AJ, Timens W, Meurs H, Maarsingh H, Schmidt M. Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease. PLoS One 2012;7:e31574.

Pera T, Atmaj C, van der Vegt M, Halayko AJ, Zaagsma J, Meurs H. Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2012;303:L272-8.

Sujeeth N, Kini RK, Shailasree S, Wallaart E, Shetty SH, Hille J. Characterization of a hydroxyproline-rich glycoprotein in pearl millet and its differential expression in response to the downy mildew pathogen Sclerospora graminicola. Acta Physiologiae Plantarum 2012;34:779-791.

Talaei F, Bouma HR, Hylkema MN, Strijkstra AM, Boerema AS, Schmidt M, Henning RH. The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster. J Exp Biol 2012;215:2912-2919.

Talaei F, Schmidt M, Henning RH. Induction of VMAT-1 and TPH-1 expression induces vesicular accumulation of serotonin and protects cells and tissue from cooling/rewarming injury. PLoS One 2012;7:e30400.

Chapter in Book:

Hendrawati O, Woerdenbag HJ, Hille J, Kayser O. Metabolic engineering of medicinal plants and microorganisms for the production of natural products. In: Kayser O and Warzecha H, editors. Pharmaceutical biotechnology: drug discovery and clinical applications, Chapter 19 ed: Wiley-VCH Verlag GmbH & Co. KGaA; 2012. p. 491-507.

Dissertations:

Baarsma HA. Glycogen synthase kinase-3 (GSK-3) and beta-catenin: potential novel therapeutic targets for COPD. 2012:1-248. Promotores: Prof. dr. H. Meurs, Prof. dr. H.A.M. Kerstjens. Copromotor: Dr. R. Gosens.

Talaei F. Modulation of endogenous H2S production. Its role in hibernation and pharmacological cell protection. 2012: Promotores: Prof. dr. R.H. Henning, Prof. dr. M. Schmidt.

Qureshi MK. Characterization of genes involved in the regulation of programmed cell death in Arabidopsis thaliana. 2012: Promotor J. Hille.

Rasul I. Characterization of the Tm-2² locus of tomato and its durability. 2012: Promotor J. Hille.