2008

Artikelen:

Gosens,R., Meurs,H., and Schmidt,M. (2008). The GSK-3/beta-catenin-signalling axis in smooth muscle and its relationship with remodelling. Naunyn-Schmiedebergs Archives of Pharmacology 378, 185-191.

Gosens,R., Roscioni,S.S., Dekkers,B.G.J., Pera,T., Schmidt,M., Schaafsma,D., Zaagsma,J., and Meurs,H. (2008). Pharmacology of airway smooth muscle proliferation. European Journal of Pharmacology 585, 385-397.

Gosens,R., Mutawe,M., Martin,S., Basu,S., Bos,S.T., Tran,T., and Halayko,A.J. (2008). Caveolae and caveolins in the respiratory system. Curr. Mol. Med. 8, 741-753.

Halayko,A.J., Tran,T., and Gosens,R. (2008). Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins. Proc. Am. Thorac. Soc. 5, 80-88.

Maarsingh,H., Zaagsma,J., and Meurs,H. (2008). Arginine homeostasis in allergic asthma. European Journal of Pharmacology 585, 375-384.

Maarsingh,H., Pera,T., and Meurs,H. (2008). Arginase and pulmonary diseases. Naunyn-Schmiedebergs Archives of Pharmacology 378, 171-184.

Maarsingh,H., Zuidhof,A.B., Bos,I.S.T., van Duin,M., Boucher,J.L., Zaagsma,J., and Meurs,H. (2008). Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation. American Journal of Respiratory and Critical Care Medicine 178, 565-573.

Meurs,H., Gosens,R., and Zaagsma,J. (2008). Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models. European Respiratory Journal 32, 487-502.

Nijholt,I.M., Dolga,A.M., Ostroveanu,A., Luiten,P.G.M., Schmidt,M., and Eisel,U.L.M. (2008). Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation. Cellular Signalling 20, 1715-1724.

Nunes,R.O., Schmidt,M., Dueck,G., Baarsma,H., Halayko,A.J., Kerstjens,H.A.M., Meurs,H., and Gosens,R. (2008). GSK-3/beta-catenin signaling axis in airway smooth muscle: role in mitogenic signaling. American Journal of Physiology-Lung Cellular and Molecular Physiology 294, L1110-L1118.

Roscioni,S.S., Elzinga,C.R., and Schmidt,M. (2008). Epac: effectors and biological functions. Naunyn Schmiedebergs Arch. Pharmacol. 377, 345-357.

Schaafsma,D., Gosens,R., Zaagsma,J., Halayko,A.J., and Meurs,H. (2008). Rho kinase inhibitors: A novel therapeutical intervention in asthma? European Journal of Pharmacology 585, 398-406.

Schaafsma,D., Bos,I.S.T., Zuidhof,A.B., Zaagsma,J., and Meurs,H. (2008). The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation. American Journal of Physiology-Lung Cellular and Molecular Physiology 295, L214-L219.

Schaafsma,D., Roscioni,S.S., Meurs,H., and Schmidt,M. (2008). Monomeric G-proteins as signal transducers in airway physiology and pathophysiology. Cellular Signalling 20, 1705-1714.

Sharma,P., Tran,T., Stelmack,G.L., McNeill,K., Gosens,R., Mutawe,M.M., Unruh,H., Gerthoffer,W.T., and Halayko,A.J. (2008). Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. American Journal of Physiology-Lung Cellular and Molecular Physiology 294, L57-L68.

Hoofdstuk uit boek:

Halayko,A.J., Gosens,R., and Tran,T. (2008). Airway smooth muscle phenotypic and functional plasticity. In Airway smooth muscle in asthma and COPD, K.F.Chung, ed. (Chichester: John Wiley & Sons Ltd.), pp. 71-88.

Patenten:

Haas, M, Kluskens, LD, Kuipers, A, Rink, R, Nelemans, SA, and Moll, GN. Cyclic angiotensin analogs. Applied Nanosystems BV (NL), Stichting Tech Wetenschapp (NL), Haas, M, Kluskens, LD, Kuipers, A, Rink, R, Nelemans, SA, and Moll, GN. WO03099862[WO2008018792]. 30-10-2008.Haas,M; Kluskens,LD; Kuipers,A; Rink,R; Nelemans,SA; Moll,GN.

Meurs, H., Zaagsma, J., Maarsingh, H., Duin van, M. Use of arginase inhibitors in the treatment of asthma and allergic rhinitis. [WO 2008/061612 A1]. 2008.

Nijholt, I.M., Schmidt, M., Modulation of memory function. [P85114US00]. 2008.

Vakpublikaties:

Maarsingh, H., Zaagsma, J., and Meurs, H. De rol van arginase in allergisch astma. Nederlands Tijdschrift voor Allergie 8[5], 163-170. 2008.

Meurs, H., Gosens, R., Maarsingh, H., and Zaagsma, J. Mechanismen van luchtweghyperreactiviteit bij allergisch astma. Folia Pharmaceutica 95[5], 14-18. 2008.

Schmidt, M., Cellulaire communicatie: Betekenis van Epac-eiwitten voor het begrijpen en behandelen van ziekten. Foliolum 12[1], oktober, 12-13. 2008.

Schmidt, M., Epac's sturen hart- en hersenprocessen. Pharmaceutisch Weekblad 144, 28-29. 2008.