Recent Theses
| Title | Promotor(s) | Co-promotor(s) | |
|---|---|---|---|
2024 |
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| Laura Bolte | Diet, microbe & immune responses | Prof. dr. R.K. Weersma, Prof. dr. G.A.P. Hospers | dr. R.J.Björk |
| Maria Camila Trillos Almanza | The art of liver healing:novel prognostic biomarkers and therapeutic approaches around liver transplantation | Prof. dr. A.J. Moshage, Prof. dr. K.N. Faber | dr. J. Blokzijl, dr. F.G.I. van Vilsteren |
| Johanna Carolina Arroyave Ospina | Cellular response mechanisms during lipotoxicity in metabolic dysfunction-associated steatotic liver disease: identification of novel therapeutic targets | Prof. dr. A.J. Moshage, Prof. dr. K.N. Faber | |
| Ruben Gabriels | Detection and molecular analysis of inflamation and malignancies in the gastro-intestinal tract | Prof. dr. W.B. Nagengast, Prof. dr. G. Dijkstra | dr. G. Kats-Ugurlu |
| Roberta Loveikyte | Iron deficiency in inflammatory bowel disease | Prof. dr. G. Dijkstra | dr. A.E. van der Meulen-de Jong |
| Marjolein Klaassen | The gut microbiome in the onset and progression of inflammatory bowel diseases | Prof. dr. R.K. Weersma, Prof. dr. A.P. Zhernakova | dr. R. Gacesa |
2023 |
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| Defu Kong | Cause and consequences of enhanced LGR5 expression in human liver cirrhosis | Prof. dr. K.N. Faber, Prof. dr. V.E. de Meijer | Dr. J. Blokzijl |
| Iris Schmidt | Quantitative fluorescence molecular endoscopy - a multidimensional approach for cancer detection | Prof. dr. W.B. Nagengast | Dr. D.J. Robinson, Dr. D. Gorpas |
| Sandra Serna Salas | Studies on the role of adrenergic antogonists in the treatment of metabolic-dysfunction associated fatty liver disease and liver fibrosis | Prof. dr. A.J. Moshage, Prof. dr. K.N. Faber | |
| Matthijs Linssen | Fluorescently labelled monoclonal antibodies for real-time molecular imaging: Pharmaceutical develpment of near-infrared tracers and their application in clinical settings | Prof. dr. W.B. Nagengast, Prof. dr. G.M. van Dam, prof. dr. G. Dijkstra | Dr. A. Jorritsma-Smit |
| Arno Bourgonje | Biomarker signatures in pathophysiology and therapeutic interventions in inflammatory bowel diseases: a multimodal approach | Prof. dr. G. Dijkstra, Prof. dr. K.N. Faber, Prof. dr. H. van Goor, Prof. dr. R.K. Weersma | |
2022 |
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| Zongmei Wu | Metabolic Dysfunction-associated Fatty Liver Disease: Mechanisms and targets for intervention | Prof. dr. A.J. Moshage, Prof. dr. G. van Dijk | |
| Xiaojuan Zhao | Developments in molecular and advanced endoscopic imaging in esophageal cancer | Prof. dr. W.B. Nagengast, Prof. dr. M.A.T.M. van Vugt | Dr. R.S.N. Fehrmann |
| Guido Trentadue | Organ-specific interventions in intestinal transplantation | Prof. dr. G. Dijkstra, Prof. Dr. K.N. Faber | Dr. J.W. Haveman, Dr. G. Kats-Ugurlu |
| Eline Wouters-van den Berg | Metabolic associated fatty liver disease: prevalence and determinants | Prof. dr. R.K. Weersma, Dr. R.P.F. Dullaart, Prof. dr. K.N. Faber | Dr. J. Blokzijl |
| Raphael Fagundes Rosa | Microenvironmental modulation of the intestinal epithelial barrier | Prof. dr. K.N. Faber, Dr. ir. H.J.M. Harmsen, Prof. dr. G. Dijkstra | |
2021 |
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| Shixian Hu | Understanding the complexity of inflammatory bowel disease from a multi-omics perspective | Prof. dr R.K. Weersma, Prof dr. J. Yang-Fu | Dr. A. Vich Vila |
| Yanni Li | Genetic and environmental effects on liver diseases | Prof. dr. R.K. Weersma, Dr. E.A.M. Festen | Dr. V.E. de Meijer |
| Alejandra Hernandez Villanueva | Role of extracellular vesicles in hypoxia-induced hepatic injury in non-alcoholic fatty liver disease | Prof. dr. A.J. Moshage, Prof. dr. M Arrese | |
| Werna Uniken Venema | Gut mucosal gene expression in inflammatory bowel disease. The heterogeneous nature of inflammation | Prof. dr. R.K. Weersma | Dr. E.A.M. Festen |
| Fabio Aguilar Mora | Targeting mitochondria to prevent diclofenac-induced liver toxicity | Prof. dr. A.J. Moshage | Prof. dr. K.N. Faber |
| Jolien Tjalma | Molecular flurorescence endoscopy: clinical development and validation within the lower gastrointestinal tract | Prof. dr. W.B. Nagengast, Prof. dr. G.A.P. Hospers, Prof. dr. J.H. Kleibeuker | |
| Floris Voskuil | Clinical application of near infrared fluorescence imaging in solid cancers: Improving surgical accuracy by lighting up tumors | Dr. M.J.H. Witjes, Prof. dr. G.M. van Dam, Prof. dr. W.B. Nagengast | |
| Kim van der Sloot | The exposome in development and behaviour of Inflammatory Bowel Disease |
Prof. dr. G. Dijkstra, Prof. dr. R.K. Weersma |
Dr. B.Z. Alizadeh |
| Vera Peters | Towards dietary assessment and interventions for patients with inflammatory bowel disease | Prof. dr. G. Dijkstra | Dr. B.Z. Alizadeh, dr. M.J.E. Campmans-Kuijpers |
| Valerie Collij | The gut microbiota and inflammatory bowel disease: From exploration to clinical translation | Prof. dr. R.K. Weersma, Prof. dr. J. Yang-Fu | Dr. A. Vich Vila |
2020 |
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| Archie Mposhi | Unravelling the molecular mechanisms underlying mitochondrial dysfunction in metabolic diseases | Prof. dr. K. N. Faber, Prof. dr. M. G. Rots | |
| Shiva Koets-Shajari | Novel strategies targeting hepatic stellate cells to reverse liver fibrosis |
Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage |
|
| Mengfan Zhang | Targetting hepatic stellate cells to prevent or reverse fibrosis |
Prof. dr. A.J. Moshage, Prof dr. K.N. Faber |
|
| Michiel Voskuil | Genomic medicine in inflammatory bowel disease |
Prof. dr. R.K. Weersma |
Dr. E.A.M. Festen |
| Turtushikh Damba | The role of the gaseous signaling molecule hydrogen sulfide in chroninc liver disease: Special emphasis on non-alcoholic fatty liver disease | Prof. dr. A.J. Moshage, Prof. dr. H. van Goor | |
| Steven de Jongh | Fluorescence-guided endoscopy and surgery: Clinical applications for optical imaging agents | Prof. dr.R.K. Weersma, Prof. dr. G.M. van Dam | Prof. dr. W.B. Nagengast |
| Yana Geng | Lipotoxicity in non-alcoholic fatty liver disease: mechanisms and prevention in experimental models |
Prof. dr. A.J. Moshage, Prof dr. K.N. Faber |
Dr. J. Blokzijl |
| Natalia Smith Cortínez | Novel molecular targets in hepatic stellate cells for the treatment of liver fibrosis | Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage | |
| Yingying Cui | Epithelial and subeoithelial players in chronic intestinal disease | Prof. dr. K.N. Faber, prof. dr. G.Dijkstra | |
| Danial Afsharzadeh | Decoding therapeutic roles of adipose tissue-derived stromal cells and their extracellular vesicles in liver disease | Prof. dr. K.N. Faber, Prof. dr. M.C. Harmsen, Prof. A. Canbay | |
2019 |
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| Arnau Vich Vila | Understanding the gut ecosystem: bugs, drugs & diseases | Prof. dr. R. Weersma, Prof. dr. A.P. Zhernakova | |
| Tobias van Haaften | Biomarkers, Models and Mechanisms of Intestinal Fibrosis | Prof. dr. P Olinga, Prof. dr. G. Dijkstra | Dr. M. Boersema |
| Ali Saeed | Disturbed vitamin A metabolism in chronic liver disease and relevance for therapy | Prof. dr. K.N. Faber | Dr. J. Blokzijl |
| Julius von Martels | Towards novel biomarkers and rational nutritional interventions in Inflammatory Bowel Disease | Prof. dr. G. Dijkstra, Prof. dr. P. de Vos, Prof. K.N. Faber | Dr. ir. H.J.M. Harmsen |
| Floris Imhann | The gut microbiome in intestinal diseases and the infrastructure to investigate it | Prof. dr. R.K. Weersma, Prof. dr. C. Wijmenga | |
2018 |
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| Lieke Spekhorst | Clinical and genetic factors associated with disease couse in inflammatory bowel disease | Prof. dr. R.K. Weersma, Prof. dr. G. Dijkstra | Dr. E.A.M. Festen |
| Wilson Alfredo Rios Ocampo | Cellular stress response during hepatitis C virus infection: a balancing act between viral persistence and host cell survival | Prof. dr. A.J. Moshage, Prof. dr. C.A.H.H. Daemen, Prof. dr. K.N. Faber, Prof. M.C. Navas | - |
| Marijn Visschedijk | Inflammatory Bowel Disease | Prof. dr. R.K. Weersma, Prof. dr. C. Wijmenga | Dr. C.C. van Diemen, Dr. E.A.M. Festen |
2016 |
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| Xueting Bai | Therapeutic effects of the traditional medicinal plant Ipomoea stolonifera for the treatment of liver diseases | Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage, Prof. dr. G. Shi | - |
2015 |
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| Mehdi Sadaghian Sadabad | Interaction between the gut and its microbiota in inflammatory bowel disease | Prof. dr. G. Dijkstra, Prof. dr. K.N. Faber | Dr. ir. H.J.M. Harmsen |
2014 |
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| Anouk Regeling | Gene-environment interactions in inflammatory bowel disease | Prof. dr. K.N. Faber, Prof. dr. G. Dijkstra | - |
| Marjolein H. Tiebosch | Antioxidant adaptations inliver fibrogenesis | Prof. dr. A.J. Moshage, Prof. dr. K.N. Faber | - |
2013 |
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| Martijn O. Hoeke | The role of vitamin A in bile acid synthesis transport and the relevance for cholestatic liver disease | Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage | |
| Krzysztof P. Rembacz | The functional relationship between peroxisomes, bile acids and lipid rafts in the liver | Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage | |
2012 |
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| Golnar Kariman | Signal Transduction Pathways in Hepatocyte Cell Death: New Targets for therapy | Prof. dr. A.J. Moshage, Prof dr. K.N. Faber | |
2011 |
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| Frans van der Heide | Studies on smoking in patients with inflammatory bowel disease and liver transplant reciepients | Prof. dr. J.H. Kleibeuker, Prof. dr. K.N. Faber | Dr. G. Dijkstra, Dr. E.B. Haagsma |
| Noortje Festen | Shared genetic background of inflammatory diseases of the bowel | Prof. dr. C. Wijmenga, Prof. dr. J.H. Kleibeuker | Dr. R.K.Weersma |
| Axel van Steenpaal | Function and regulation of the multidrug resistance-associated protein 1 during inflammatory bowel disease and liver regeneration | Prof. dr. K.N. Faber, Prof. dr. A.J. Moshage | Dr. G. Dijkstra |
2010 |
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| Lu Zhou | Inflammatory Bowel Diseases from Genetics to Immunology | Prof. dr. K.N. Faber, Prof. dr. M.P. Peppelenbosch | Dr. G. Dijkstra, Dr. R.K.Weersma |
2009 |
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| Jannes Woudenberg | Novel aspects of peroxisome composition and function in the liver | Prof. dr. A.J. Moshage | Dr. K.N. Faber |
2008 |
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| Sandra Dunning | Resistance of activated stellate cells to cell death in liver fibrosis: mechanisms and targets for intervention | Prof. dr. A.J. Moshage | Dr. K.N. Faber |
| Antonella Pellicoro | Hepatic peroxisome function in health and disease | Prof. dr. P.L.M. Jansen, Dr. K.N. Faber | |
| Hans Blokzijl | Functional regulation of transport proteins in gastrointestinal and liver disease | Prof. dr. P.L.M. Jansen, Prof. dr. A.J. Moshage | Dr. K.N.Faber, Dr. G. Dijkstra |
| Titia Vrenken | Mechanisms and prevention of hepatocyte cell death | Prof. dr. A.J. Moshage | |
2007 |
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| Rinse Weersma | Genetic susceptibility for inflammatory bowel diseases. | Prof. dr. J.H. Kleibeuker, Prof. dr. C. Wijmenga | |
| Robert Verdonk | Complications after liver transplantation: A focus on bowel and bile ducts. | Prof. dr. J.H. Kleibeuker | Dr. E.B. Haagsma, Dr. G. Dijkstra, Dr. R.J. Porte |
2006 |
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| Laura Conde de la Rosa | Mechanisms of oxidative stress-induced cell death in hepatocytes: Targets for protective intervention | Prof. dr. A.J. Moshage, Prof. dr. P.L.M. Jansen | |
| Mathilde Jalving | Apoptosis pathways in (pre)maligant gastrointestinal tumours: potentials for intervention | Prof. dr. J.H. Kleibeuker, Prof. dr. E.G.E. de Vries | Dr. S. de Jong, Dr. J.J. Koornstra, Dr. J. Wesseling |
| Fleur E.M. Rijcken | Hereditary nonpolyposis colorectal cancer. Studies on tumor development and preventive stratagies. | Prof. dr. H. Hollema, Prof. dr. J.H. Kleibeuker, Prof. dr. A. van der Zee | |
| Liekele E. Oostenbrug | Low penetrance susceptibility genes in inflammatory bowel disease | Prof. dr. P.L.M. Jansen, Prof. dr. J.H. Kleibeuker | Dr. ir. G.J. te Meerman, Dr. H.M. van Dullemen |
| Jan Jacob Koornstra | Apoptosis and colorectal cancer. Studies on pathogenesis and potential therapeutic targets | Prof. dr. H. Hollema, Prof. dr. J.H. Kleibeuker, Prof. dr. E.G.E. de Vries | Dr. S.de Jong |
2005 |
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| Jacqueline Plass | Function and regulation of the human bile salt export pump | Prof.dr. P.L.M. Jansen | Dr. K.N.Faber |
| Mirjam de Jong | Identification of genes other than the high-penetrance genes involved in colorectal and/or breast cancer susceptibility | Prof. dr. J.H. Kleibeuker, Prof. dr. E.G.E. de Vries | dr. G.J. te Meerman, dr. W.T.A. de Graaf |
2004 |
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| Janneke van der Woude | Apoptosis in (pre) malignant lesions in the gastro-intestinal tract | Prof. dr. P.L.M. Jansen, Prof. dr. J.H. Kleibeuker | Dr. A.J. Moshage |
| Marieke Schoemaker | Apoptotic cell death as a target for the treatment of acute and chronic liver injury | Prof. dr. P.L.M. Jansen, Prof. dr. H.J. Haisma | Dr. A.J. Moshage, Dr. K. Poelstra |
| Gerard Dijkstra | Inducible nitric oxide synthase in intestinal inflammation | Prof. dr. P.L.M. Jansen | Dr. A.J. Moshage, Dr. H van Goor |
2003 |
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| Maran Berends | Towards optimal identification of carriers of germline mutations involved in mismatch repair | ||
| Laurens van der Waaij | The interaction between the mucosal system and the commensal microflora of the colon | Prof. dr. P.L.M. Jansen, Prof, dr. F.G.M. Kroese | |
2002 |
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| Leo Meerman | The power of purple, protoporphyrins in the liver | ||
| Jenny Ros | Expression and regulation of ABC transporter genes during liver regeneration | Prof. dr. P.L.M. Jansen, Prof. dr. M. Müller | |
2000 |
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| Johan Renes | (Patho)physiological function of the multidrug resistance protein MRP1 | Prof. dr. P.L.M. Jansen, Prof. dr.E.G.E. de Vries | Dr. M. Müller |
| Guido Hooiveld | P-glycoproteins and hepatiobiliary secretion, studies on cloning, function, and expression | Prof. dr. D.K.F. Meijer, Prof. dr. P.L.M. Jansen | Dr. M. Müller |
1999 |
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| Thera Vos | Regulation of the hepatic expression of iNOS and ABC-transporters | ||
1995 |
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| Reint Huizenga | Ammonia in human fluids methodology and clinical applications | ||
| Ids Klompmaker | Clinical Aspects of immunosuppression in liver transplantation | ||
| Last modified: | 22 October 2024 12.43 p.m. |