Immune Regulation and Ageing

The research group Immune Regulation and Ageing focuses on (patho)physiological aspects of the ageing immune system. Specifically, We study the molecular mechanisms involved in the deterioration of immune function associated with ageing and autoimmunity.

Research themes

1)What factors contribute to age-related immunosenescence and how do these factors deviate from normal immune-aging

2)How can patients at risk be recognized, e.g. what are the indicators that relate to the development of immunosenescence and ensuing chronic diseases.

3)What are the mechanistic fundaments of the age related aggregation of risk factors, e.g. what age related molecular mechanisms are instrumental for the development of immunosenescence and ensuing chronic diseases.

4)How can we expand immune-longevity and prevent the development of immunosenescence and ensuing chronic diseases or multiple morbidity.