R.E.H. (Ruby) Karsten

PhD Student

Faculty of Science and Engineering

Telephone:

E-mail:

r.e.h.karsten rug.nl

ORCID Research Portal

Publications

Studying the intracellular bile acid concentration and toxicity in drug-induced cholestasis: Comprehensive LC-MS/MS analysis with human liver slices

Karsten, R. E. H., Gier, K., de Meijer, V. E., Huibers, W. H. C., Permentier, H. P., Verpoorte, E. & Olinga, P., Apr-2025, In: Toxicology in Vitro. 104, 106011.

Research output: Contribution to journal › Article › Academic › peer-review

Real-Time Monitoring of Oxygen-Consumption Rate in Mouse Liver Slices Incubated in Organ-on-a-Chip Devices

Karsten, R. E. H., Gier, K., Mulder, J.-P. S. H., Grajewski, M., Olinga, P. & Verpoorte, E., 30-Sept-2024, In: Analytical Chemistry. 96, p. 15871-15879 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

The liver's (mal)functions magnified

Karsten, R., 2024, [Groningen]: University of Groningen. 204 p.

Research output: Thesis › Thesis fully internal (DIV)

Polystyrene lung-on-a-chip model for oxygen metabolism studies

de Haan, P., Mulder, J.-P., Karsten, R., Ahmed, M., Pijnenburg, M., Nagelkerke, A., Heijink, I. & Verpoorte, E., 17-Oct-2023, p. 3112. 2 p.

Research output: Contribution to conference › Paper › Academic

Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis

Karsten, R. E. H., Krijnen, N. J. W., Maho, W., Permentier, H., Verpoorte, E. & Olinga, P., Sept-2022, In: Archives of toxicology. 96, 9, p. 2523-2543 21 p.

Research output: Contribution to journal › Article › Academic › peer-review

Real-Time, In-Line Monitoring of Oxygen-Dependent Metabolism of Mouse Precision-Cut Liver Slices Incubated in a Microfluidic Device

Karsten, R. E. H., Grajewski, M., Mulder, J. P. S. H., Olinga, P. & Verpoorte, E., 2021, MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society , Vol. 1. p. 503-504 2 p. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Ex Vivo Model in Cholestasis Research

Karsten, R. E. H., Oosterhuis, D., van Wijk, L. A. & Olinga, P., 2019, Experimental Cholestasis Research. Vinken, M. (ed.). New York: Humana Press, p. 351-362 12 p. (Methods in Molecular Biology; vol. 1981).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Micro magnetic resonance imaging of murine liver tissue slices on a microfluidic perfusion device

Sharma, M., Patra, B., Hale, W., Karsten, R. E. H., Salentijn, G. I. J., Grajewski, M., Fuhrer, E., Zakhurdaeva, A., Mager, D., Korvink, J., Olinga, P., Verpoorte, E. & Utz, M., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society , p. 1722-1724 3 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Real-time monitoring of biliary transport in precision-cut liver slices

Grajewski, M., Salentijn, G. I. J., Karsten, R. E. H., Olinga, P. & Verpoorte, E., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society , p. 1644-1646 3 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

All (9) publications

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