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Publications

A review on the role of extrapolation as basis for paediatric marketing authorization applications of medicines in the EU

A Pooled Pharmacokinetic Analysis for Piperacillin/Tazobactam Across Different Patient Populations: From Premature Infants to the Elderly

EMA perspective on the value of model-informed drug development for labeling recommendations regarding medicine use during pregnancy and breastfeeding

Population Pharmacokinetic Modelling of Norepinephrine in Healthy Volunteers Prior to and During General Anesthesia

Target-controlled Infusion of Remimazolam in Healthy Volunteers Shows Some Acute Tolerance

A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients

Development of a pharmacokinetic and pharmacodynamic model for intranasal administration of midazolam in older adults: a single-site two-period crossover study

Gentamicin Administration in Dialysis Patients: Before or After Hemodialysis?

Moving Toward a Question-Centric Approach for Regulatory Decision Making in the Context of Drug Assessment

Pharmacodynamic Effects of Norepinephrine in a Cross-Over Study with Awake and Anesthetized Healthy Volunteers

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