dr. M. (Marco) de Bruyn

Associate professor

Faculty of Medical Sciences

Telephone:

+31 50 361 3174

E-mail:

m.de.bruyn umcg.nl

Homepage ORCID Research Portal

Publications

Vvax001, a Therapeutic Vaccine for Patients with HPV16-positive High-grade Cervical Intraepithelial Neoplasia: a Phase II Trial

Eerkens, A. L., Esajas, M. D., Brummel, K., Vledder, A., van Rooij, N., Plat, A., Avalos Haro, S. B., Paijens, S. T., Slagter-Menkema, L., Schuuring, E., Werner, N., Kosterink, J. G. W., Kroesen, B.-J., Wilschut, J. C., Daemen, T., Bart, J., Nijman, H. W., de Bruyn, M. & Yigit, R., 24-Jan-2025, (E-pub ahead of print) In: Clinical Cancer Research.

Research output: Contribution to journal › Article › Academic › peer-review

128P - Whole blood transcriptomics identifies transcriptional patterns linked to outcomes in patients receiving immune checkpoint inhibitors

Hone Lopez, S., Loipfinger, S., Bhattacharya, A., Jalving, M., Oosting, S. F., Hiltermann, J., de Bruyn, M., de Vries, E. G. E., de Haan, J.-J. & Fehrmann, R., 14-Sept-2024, In: Annals of Oncology. 35, Supplement 2, p. S266 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

B cells critical for outcome in high grade serous ovarian carcinoma

Vledder, A., Paijens, S. T., Loiero, D., Maagdenberg, A., Duiker, E. W., Bart, J., Hendriks, A. M., Jalving, M., Werner, N., van Rooij, N., Plat, A., Wisman, G. B. A., Yigit, R., Roelofsen, T., Kruse, A. J., de Lange, N. M., Koelzer, V. H., de Bruyn, M. & Nijman, H. W., 15-Dec-2024, In: International Journal of Cancer. 155, 12, p. 2265-2276 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Biomarker and transcriptomics profiles of serum selenium concentrations in patients with heart failure are associated with immunoregulatory processes

Al-Mubarak, A. A., Markousis Mavrogenis, G., Guo, X., De Bruyn, M., Nath, M., Romaine, S. P. R., Grote Beverborg, N., Arevalo Gomez, K., Zijlstra, S. N., van Veldhuisen, D. J., Samani, N. J., Voors, A. A., van der Meer, P. & Bomer, N., Apr-2024, In: Redox Biology. 70, 10 p., 103046.

Research output: Contribution to journal › Article › Academic › peer-review

Correction to: Prediction of recurrence risk in endometrial cancer with multimodal deep learning (Nature Medicine, (2024), 10.1038/s41591-024-02993-w)

Volinsky-Fremond, S., Horeweg, N., Andani, S., Barkey Wolf, J., Lafarge, M. W., de Kroon, C. D., Ørtoft, G., Høgdall, E., Dijkstra, J., Jobsen, J. J., Lutgens, L. C. H. W., Powell, M. E., Mileshkin, L. R., Mackay, H., Leary, A., Katsaros, D., Nijman, H. W., de Boer, S. M., Nout, R. A. & de Bruyn, M.& 5 others, Church, D., Smit, V. T. H. B. M., Creutzberg, C. L., Koelzer, V. H. & Bosse, T., Jul-2024, In: Nature Medicine. 30, 7, p. 2092 1 p.

Research output: Contribution to journal › Erratum

Genomic instability as a driver and suppressor of anti-tumor immunity

Requesens, M., Foijer, F., Nijman, H. W. & de Bruyn, M., 2024, In: Frontiers in Immunology. 15, 24 p., 1462496.

Research output: Contribution to journal › Review article › peer-review

Immune predictors of response to immune checkpoint inhibitors in mismatch repair-deficient endometrial cancer

Grau Bejar, J. F., Yaniz Galende, E., Zeng, Q., Genestie, C., Rouleau, E., de Bruyn, M., Klein, C., Le Formal, A., Edmond, E., Moreau, M., Plat, A., Gouy, S., Maulard, A., Pautier, P., Michels, J., Oaknin, A., Colomba-Blameble, E. & Leary, A., 1-Jul-2024, In: Journal for immunotherapy of cancer. 12, 7, 15 p., e009143.

Research output: Contribution to journal › Article › Academic › peer-review

ImmunoPET provides a novel way to visualize the CD103+ tissue-resident memory T cell to predict the response of immune checkpoint inhibitors.

Fan, X., Nijman, H. W., de Bruyn, M. & Elsinga, P. H., 5-Jan-2024, In: EJNMMI Research. 14, 1, 11 p., 5.

Research output: Contribution to journal › Review article › peer-review

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study

Eerkens, A. L., Brummel, K., Vledder, A., Paijens, S. T., Requesens, M., Loiero, D., van Rooij, N., Plat, A., Haan, F.-J., Klok, P., Yigit, R., Roelofsen, T., de Lange, N. M., Klomp, R., Church, D., Ter Elst, A., Wardenaar, R., Spierings, D., Foijer, F. & Koelzer, V. H.& 6 others, Bosse, T., Bart, J., Jalving, M., Reyners, A. K. L., de Bruyn, M. & Nijman, H. W., Dec-2024, In: Nature Communications. 15, 17 p., 7695.

Research output: Contribution to journal › Article › Academic › peer-review