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About us Practical matters How to find us K. (Karim) Rafie, PhD

K. (Karim) Rafie, PhD

Assistant Professor, Pharmacology of host-pathogen interactions

Faculty of Science and Engineering

Telephone:

+31 50 36 39718

E-mail:

k.rafie rug.nl

ORCID Research Portal

Publications

The structure of enteric human adenovirus 41—A leading cause of diarrhea in children

Rafie, K., Lenman, A., Fuchs, J., Rajan, A., Arnberg, N. & Carlson, L.-A., 6-Jan-2021, In: Science Advances. 7, 2, 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46

Persson, B. D., John, L., Rafie, K., Strebl, M., Frängsmyr, L., Ballmann, M. Z., Mindler, K., Havenga, M., Lemckert, A., Stehle, T., Carlson, L.-A. & Arnberg, N., 19-Jan-2021, In: Proceedings of the National Academy of Sciences. 118, 3, 8 p., e2020732118.

Research output: Contribution to journal › Article › Academic › peer-review

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, K.-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., Aalten, D. M. F. V. & Virdee, S., Apr-2018, In: Nature. 556, p. 381-385 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

Rafie, K., Raimi, O., Ferenbach, A. T., Borodkin, V. S., Kapuria, V. & van Aalten, D. M. F., 2017, In: Open Biology. 7, 6, 9 p., 70078.

Research output: Contribution to journal › Article › Academic › peer-review

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

Pathak, S., Alonso, J., Schimpl, M., Rafie, K., Blair, D. E., Borodkin, V. S., Schüttelkopf, A. W., Albarbarawi, O. & Aalten, D. M. F. V., Sept-2015, In: Nature Structural & Molecular Biology. 22, p. 744–750 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Thio-linked UDP-peptide conjugates as O-GlcNAc transferase inhibitors

Rafie, K., Gorelik, A., Trapannone, R., Borodkin, V. S. & van Aalten, D. M. F., 3-May-2018, In: BIOCONJUGATE CHEMISTRY. 29, 6, p. 1834–1840 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry

Borodkin, V. S., Rafie, K., Selvan, N., Aristotelous, T., Navratilova, I., Ferenbach, A. T. & van Aalten, D. M. F., 11-Apr-2018, In: ACS chemical biology. 13, 5, p. 1353–1360 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Altered Extracellular Vesicle-Derived Protein and microRNA Signatures in Bronchoalveolar Lavage Fluid from Patients with Chronic Obstructive Pulmonary Disease

Bartel, S., Wolters, J. C., Noor, H., Rafie, K., Fang, J., Kirchner, B., Nolte-T Hoen, E., Pfaffl, M. W., Rutgers, S., Timens, W., van den Berge, M. & Hylkema, M. N., 30-May-2024, In: Cells. 13, 11, 21 p., 945.

Research output: Contribution to journal › Article › Academic › peer-review

Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation

Kumar, P., Schexnaydre, E., Rafie, K., Kurata, T., Terenin, I., Hauryliuk, V. & Carlson, L. A., Jan-2022, In: FEBS Letters. 596, 9, p. 1203-1213 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

UDP-GlcNAc Analogs as Inhibitors of O-GlcNAc Transferase (OGT): Spectroscopic, Computational and Biological Studies.

Merino, P., Ghirardello, M., Perrone, D., Chinaglia, N., Sadaba, D., Delso, I., Tejero, T., Marchesi, E., Fogagnolo, M., Rafie, K. & van Aalten, D. M. F., 2018, In: Chemistry – A European Journal. 24, 28, p. 7264-7272 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (13) publications

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