K.M. (Katarzyna (Kasia)) Tych, PhD

Faculteit Science and Engineering

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ORCID Research Portal

Publicaties

Impact of Ligand-Induced Oligomer Dissociation on Enzyme Diffusion, Directly Observed at the Single-Molecule Level

Yancheva, Y. D., Kaya, S. G., Belyy, A., Fraaije, M. W. & Tych, K. M., 12-feb.-2025, In: Nano Letters. 25, 6, blz. 2373–2380 8 blz., 4c05792.

Onderzoeksoutput: Article › › peer review

Nanopore-Functionalized Hybrid Lipid-Block Copolymer Membranes Allow Efficient Single-Molecule Sampling and Stable Sensing of Human Serum

Vreeker, E., Grünewald, F., van der Heide, N. J., Bonini, A., Marrink, S. J., Tych, K. K. & Maglia, G., 4-mrt.-2025, (E-pub ahead of print) In: Advanced materials. 15 blz., e2418462.

Onderzoeksoutput: Article › › peer review

One-pot dual protein labeling for simultaneous mechanical and fluorescent readouts in optical tweezers

Silbermann, L.-M., Fottner, M., van der Meulen, R., Migdad, N., Lang, K. & Tych, K., apr.-2025, In: Protein Science. 34, 4, 13 blz., e70098.

Onderzoeksoutput: Article › › peer review

Blobs form during the single-file transport of proteins across nanopores

Sauciuc, A., Whittaker, J., Tadema, M., Tych, K., Guskov, A. & Maglia, G., 12-sep.-2024, In: Proceedings of the National Academy of Sciences. 121, 38, 10 blz., e2405018121.

Onderzoeksoutput: Article › › peer review

Exerting pulling forces in fluids by directional disassembly of microcrystalline fibres

Pantaleone, L. C., Calicchia, E., Martinelli, J., Stuart, M. C. A., Lopatina, Y. Y., Browne, W. R., Portale, G., Tych, K. M. & Kudernac, T., okt.-2024, In: Nature Nanotechnology. 19, 10, blz. 1507–1513 7 blz.

Onderzoeksoutput: Article › › peer review

Probing the stability and interdomain interactions in the ABC transporter OpuA using single-molecule optical tweezers

van der Sleen, L., Stevens, J. A., Marrink, S. J., Poolman, B. & Tych, K., 23-apr.-2024, In: Cell reports. 43, 4, 19 blz., 114110.

Onderzoeksoutput: Article › › peer review

The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA

Marinus, T., Foster, T. L. & Tych, K. M., apr.-2024, In: Biochemical Society Transactions. 52, 2, 11 blz., 20231232.

Onderzoeksoutput: Article › › peer review

The known unknowns of the Hsp90 chaperone

Silbermann, L.-M., Vermeer, B., Schmid, S. & Tych, K., 31-dec.-2024, In: eLife. 13, 21 blz., e102666.

Onderzoeksoutput › peer review

Unravelled proteins form blobs during translocation across nanopores

Sauciuc, A., Whittaker, J., Tadema, M., Tych, K., Guskov, A. & Maglia, G., 25-jan.-2024, (Submitted) 11 blz. (bioRxiv).

Onderzoeksoutput: Voordruk ›

Aha1 regulates Hsp90's conformation and function in a stoichiometry-dependent way

Mondol, T., Silbermann, L.-M., Schimpf, J., Vollmar, L., Hermann, B., Tych, K. K. & Hugel, T., 5-sep.-2023, In: Biophysical Journal. 122, 17, blz. 3458-3468 22 blz.

Onderzoeksoutput: Article › › peer review