prof. dr. J.W. (Hans) Jonker

Professor

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 1261

E-mail:

j.w.jonker umcg.nl

Homepage ORCID Research Portal

Publicaties

Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach

Palasantzas, V. E. J. M., Struik, D., Bos, T., Withoff, S., Fu, J., Jonker, J. W. & Hoogerland, J. A., 24-jan.-2026, In: Nutrients. 18, 3

Onderzoeksoutput: Article › › peer review

FGF1 ameliorates hepatic steatosis through acute activation of the unfolded protein response and VLDL production

van Zutphen, T., Struik, D., Liu, W., Liu, S., Sermikli, B. P., Wolters, J. C., Verkade, H. J., Atkins, A. R., Downes, M., Evans, R. M. & Jonker, J. W., feb.-2026, In: JHEP Reports. 8, 2, 13 blz., 101660.

Onderzoeksoutput: Article › › peer review

Beta-Klotho Protein Expression in Healthy Human Tissues and Liver Biopsies From Patients With MASLD or MASH

Aaldijk, A., Struik, D., Driessen, S., Verzijl, C., Verheij, J., Nieuwdorp, M., Eilers, R., Wolters, J. C., Holleboom, A. G. & Jonker, H., 2025, In: Gastro Hep Advances. 4, 10, 14 blz., 100745.

Onderzoeksoutput: Article › › peer review

Characteristics and outcomes of people with cystic fibrosis on the Eurotransplant liver transplantation waiting list

van der Spek, M. I., Verkade, H. J., Jonker, J. W., de Meijer, V. E. & Bodewes, F. A. J. A., sep.-2025, In: Journal of Cystic Fibrosis. 24, 5, blz. 991-997 7 blz.

Onderzoeksoutput: Article › › peer review

Divergent regulation of cellular cholesterol metabolism by seaweed-derived fucosterol and saringosterol

Zhan, N., Martens, N., Li, Y., Voortman, G., Leijten, F., Friedrichs, S., Caspers, M. P. M., Verschuren, L., Vanmierlo, T., Smit, M., Kuipers, F., Jonker, J. W., Bloks, V. W., Palumbo, M., Zimetti, F., Adorni, M. P., Liu, H., Lütjohann, D. & Mulder, M. T., 2025, In: Frontiers in Marine Science. 12, 1728727.

Onderzoeksoutput: Article › › peer review

Docosahexaenoic acid prevents peroxisomal and mitochondrial protein loss in a murine hepatic organoid model of severe malnutrition

Horcas-Nieto, J. M., Rios-Ocampo, W. A., Langelaar-Makkinje, M., de Boer, R., Gerding, A., Chornyi, S., Martini, I. A., Wolters, J. C., Wanders, R. J. A., Waterham, H. R., Van der Klei, I. J., Bandsma, R. H. J., Jonker, J. W. & Bakker, B. M., aug.-2025, In: Biochimica et biophysica acta-Molecular basis of disease. 1871, 6, 12 blz., 167849.

Onderzoeksoutput: Article › › peer review

Role for the liver X receptor agonist 22-ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

Martens, N., Zhan, N., Yam, S. C., Palumbo, M., Pontini, L., Leijten, F. P. J., van Vark-van der Zee, L., Voortman, G., Friedrichs, S., Gerding, A., Marinozzi, M., Jonker, J. W., Kuipers, F., Lütjohann, D., Vanmierlo, T. & Mulder, M. T., aug.-2025, In: British Journal of Pharmacology. 182, 16, blz. 3744-3766 23 blz.

Onderzoeksoutput: Article › › peer review

Supplementation of Seaweed Extracts to the Diet Reduces Symptoms of Alzheimer's Disease in the APPswePS1ΔE9 Mouse Model

Martens, N., Zhan, N., Yam, S. C., Leijten, F. P. J., Palumbo, M., Caspers, M., Tiane, A., Friedrichs, S., Li, Y., van Vark-van der Zee, L., Voortman, G., Zimetti, F., Jaarsma, D., Verschuren, L., Jonker, J. W., Kuipers, F., Lütjohann, D., Vanmierlo, T. & Mulder, M. T., 25-mei-2024, In: Nutrients. 16, 11, 36 blz., 1614.

Onderzoeksoutput: Article › › peer review

Treatment of intestinal and liver features in cystic fibrosis mice by the osmotic laxative polyethylene glycol

Bertolini, A., Bloks, V. W., Wilmink, M., Bos, E., Eilers, R., Prins, S., van de Peppel, I. P., Thomas, R., de Bruin, A., Verkade, H. & Jonker, J. W., mei-2024, In: Journal of Cystic Fibrosis. 23, 3, blz. 461-473 13 blz.

Onderzoeksoutput: Article › › peer review

Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease?

Martens, N., Zhan, N., Voortman, G., Leijten, F. P. J., van Rheenen, C., van Leerdam, S., Geng, X., Huybrechts, M., Liu, H., Jonker, J. W., Kuipers, F., Lütjohann, D., Vanmierlo, T. & Mulder, M. T., 30-jun.-2023, In: Nutrients. 15, 13, 24 blz., 3004.

Onderzoeksoutput: Article › › peer review