prof. dr. J.W. (Hans) Jonker

Professor

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 1261

E-mail:

j.w.jonker umcg.nl

Homepage ORCID Research Portal

Publicaties

Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach

Palasantzas, V. E. J. M., Struik, D., Bos, T., Withoff, S., Fu, J., Jonker, J. W. & Hoogerland, J. A., 24-jan.-2026, In: Nutrients. 18, 3, 32 blz.

Onderzoeksoutput › › peer review

FGF1 ameliorates hepatic steatosis through acute activation of the unfolded protein response and VLDL production

van Zutphen, T., Struik, D., Liu, W., Liu, S., Sermikli, B. P., Wolters, J. C., Verkade, H. J., Atkins, A. R., Downes, M., Evans, R. M. & Jonker, J. W., feb.-2026, In: JHEP Reports. 8, 2, 13 blz., 101660.

Onderzoeksoutput › › peer review

FGF1 orchestrates circadian hepatic triglyceride secretion

Sermikli, B. P., Liu, S., Kim, K., Hases, L., van Zutphen, T., Untereiner, A., Torres, J., He, M., Crossley, L., Dai, Y., Zhu, J., Koopari, C. L., Fan, W., Truitt, M. L., Jonker, J. W., Atkins, A. R., Downes, M. & Evans, R. M., 19-mrt.-2026, (E-pub ahead of print) In: Nature Communications.

Onderzoeksoutput › › peer review

Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation

Verzijl, C. R. C., Struik, D., Gerding, A., Eilers, R. E., Thomas, R. E., Koster, M., Langelaar-Makkinje, M., Smit, M., Huijkman, N., Havinga, R., Kloosterhuis, N., Bloks, V. W., Wolters, J. C., de Boer, J. F., van de Sluis, B., Bakker, B. M. & Jonker, J. W., 2026, In: Gastro Hep Advances. 5, 4, blz. 100881

Onderzoeksoutput › › peer review

Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation

Onderzoeksoutput › › peer review

Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MASH

Guo, Q., Satthawiwat, N., Sano, A., Meroueh, C., Hamdi, A., Dai, X., Warasnhe, K., Washington, A. M., Starlinger, P. P., Krivonos, A., Cao, S., Kostallari, E., Jonker, J. W., van de Sluis, B., Hamdan, F. H. & Ibrahim, S. H., 15-apr.-2026, (E-pub ahead of print) In: Hepatology (Baltimore, Md.).

Onderzoeksoutput › › peer review

VPS35 controls hepatocellular proliferation through SRC signalling and promotes diethyl nitrosamine-induced tumor initiation

Barbosa, M. G., Vos, D. Y., Verzijl, C. R. C., Heida, A. H., Bakker, M., Kloosterhuis, N. J., Koster, M. H., Smit, M., Fajardo, A., Struik, D., Olinga, P., Jonker, J. W., Thomas, R., Pol, A., de Meijer, V., Moles, A., Tharehalli, U., Kuivenhoven, J. A. & van de Sluis, B., 4-mei-2026, (E-pub ahead of print) In: Cellular and molecular gastroenterology and hepatology. blz. 101788

Onderzoeksoutput › › peer review

Beta-Klotho Protein Expression in Healthy Human Tissues and Liver Biopsies From Patients With MASLD or MASH

Aaldijk, A., Struik, D., Driessen, S., Verzijl, C., Verheij, J., Nieuwdorp, M., Eilers, R., Wolters, J. C., Holleboom, A. G. & Jonker, H., 2025, In: Gastro Hep Advances. 4, 10, 14 blz., 100745.

Onderzoeksoutput › › peer review

Characteristics and outcomes of people with cystic fibrosis on the Eurotransplant liver transplantation waiting list

van der Spek, M. I., Verkade, H. J., Jonker, J. W., de Meijer, V. E. & Bodewes, F. A. J. A., sep.-2025, In: Journal of Cystic Fibrosis. 24, 5, blz. 991-997 7 blz.

Onderzoeksoutput › › peer review

Divergent regulation of cellular cholesterol metabolism by seaweed-derived fucosterol and saringosterol

Zhan, N., Martens, N., Li, Y., Voortman, G., Leijten, F., Friedrichs, S., Caspers, M. P. M., Verschuren, L., Vanmierlo, T., Smit, M., Kuipers, F., Jonker, J. W., Bloks, V. W., Palumbo, M., Zimetti, F., Adorni, M. P., Liu, H., Lütjohann, D. & Mulder, M. T., 2-dec.-2025, In: Frontiers in Marine Science. 12, 18 blz., 1728727.

Onderzoeksoutput › › peer review