I. Manfredonia, MSc

Faculty of Science and Engineering

Telephone:

+31 50 36 34468

E-mail:

i.manfredonia rug.nl

ORCID Research Portal

Research interests

PhD project: RNA secondary structures in the evolution of Flaviviruses

Thanks to their error-prone RNA polymerases, Flaviviruses exist in their hosts as genetically diversified populations of related genomes. In arthropod-borne flaviviruses (ssRNA+ viruses) which normally switch between arthropod and human hosts, the viral population is cyclically exposed to different and strong evolutionary forces. Among all the factors contributing to viral evolution, I’m interested in RNA secondary structures.

Publications

Genome-scale deconvolution of RNA structure ensembles

Morandi, E., Manfredonia, I., Simon, L. M., Anselmi, F., van Hemert, M. J., Oliviero, S. & Incarnato, D., Feb-2021, In: Nature Methods. 18, p. 249-252 4 p., s41592-021-01075-w.

Research output: Contribution to journal › Article › Academic › peer-review

RNA Post-Transcriptional Modification Mapping Data Analysis Using RNA Framework

Manfredonia, I. & Incarnato, D., 4-Jun-2021, RNA Modifications. Methods in Molecular Biology. McMahon, M. (ed.). Springer, p. 3-13 11 p. (Methods in Molecular Biology; vol. 2298).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Structure and regulation of coronavirus genomes: State-of-the-art and novel insights from SARS-CoV-2 studies

Manfredonia, I. & Incarnato, D., Mar-2021, In: Biochemical Society Transactions. 49, 1, p. 341-352 12 p., BST20200670.

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

Manfredonia, I., Nithin, C., Ponce-Salvatierra, A., Ghosh, P., Wirecki, T. K., Marinus, T., Ogando, N. S., Snijder, E. J., van Hemert, M. J., Bujnicki, J. M. & Incarnato, D., 16-Dec-2020, In: Nucleic Acids Research. 48, 22, p. 12436-12452 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (4) publications

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