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About us Practical matters How to find us I.A. (Izabela) Rodenhuis-Zybert

University Medical Center Groningen

I.A. (Izabela) Rodenhuis-Zybert

Assistant Professor

Faculty of Medical Sciences

Telephone:

+31 50 361 6563

E-mail:

i.a.rodenhuis-zybert umcg.nl

ORCID Research Portal

Research interests

My team within the Experimental Virology Group focuses on immune mechanisms triggered by acute viral infections. Specifically, we try to understand the mechanisms governing the differences between the balanced and unbalanced inflammation induced by the infections. Currently, our primary goal is to identify points of control in inflammation in the course of dengue virus, chikungunya virus and SARS-CoV-2 infection. Importantly, through national and international collaborations with basic and clinical scientists, we foster the multidisciplinary approach to these infections.

Next to research, I enjoy teaching biology of viral infections. Herewith I hope to excite new generations to pursue science in the fields of virology and immunology.

Publications

Delineating sex-specific circulating host response signatures associated with COVID-19 severity and mortality

Keur, N., Flikweert, A. W., Ricaño-Ponce, I., Muller Kobold, A. C., van der Sar-van der Brugge, S., Rodenhuis-Zybert, I. A., Le, K. T. T., van Meurs, M., Grootenboers, M. J., van der Voort, P. H. J., Heeringa, P., Kumar, V. & Moser, J., 15-Nov-2024, In: Iscience. 27, 11, 13 p., 111150.

Research output: Contribution to journal › Article › Academic › peer-review

Interleukin 27, like interferons, activates JAK-STAT signaling and promotes pro-inflammatory and antiviral states that interfere with dengue and chikungunya viruses replication in human macrophages

Valdés-López, J. F., Hernández-Sarmiento, L. J., Tamayo-Molina, Y. S., Velilla-Hernández, P. A., Rodenhuis-Zybert, I. A. & Urcuqui-Inchima, S., 24-Apr-2024, In: Frontiers in Immunology. 15, 21 p., 1385473.

Research output: Contribution to journal › Article › Academic › peer-review

Characterization of soluble TLR2 and CD14 levels during acute dengue virus infection

Upasani, V., Ter Ellen, B. M., Sann, S., Lay, S., Heng, S., Laurent, D., Ly, S., Duong, V., Dussart, P., Smit, J. M., Cantaert, T. & Rodenhuis-Zybert, I. A., Jun-2023, In: Heliyon. 9, 6, 9 p., e17265.

Research output: Contribution to journal › Article › Academic › peer-review

Circulating adipokine levels and COVID-19 severity in hospitalized patients

Flikweert, A. W., Kobold, A. C. M., van der Sar-van der Brugge, S., Heeringa, P., Rodenhuis-Zybert, I. A., Bijzet, J., Tami, A., van der Gun, B. T. F., Wold, K. I., Huckriede, A., Franke, H., Emmen, J. M. A., Emous, M., Grootenboers, M. J. J. H., van Meurs, M., van der Voort, P. H. J. & Moser, J., Feb-2023, In: International Journal of Obesity. 47, p. 126-137 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue

Moser, J., Emous, M., Heeringa, P. & Rodenhuis-Zybert, I. A., Nov-2023, In: Trends in Endocrinology & Metabolism. 34, 11, p. 735-748 14 p.

Research output: Contribution to journal › Review article › peer-review

Applying NV center-based quantum sensing to study intracellular free radical response upon viral infections

Wu, K., Vedelaar, T. A., Damle, V. G., Morita, A., Mougnaud, J., Reyes San Martin, C., Zhang, Y., van der Pol, D. P. I., Ende-Metselaar, H., Rodenhuis-Zybert, I. & Schirhagl, R., 1-Jun-2022, In: Redox Biology. 52, 11 p., 102279.

Research output: Contribution to journal › Article › Academic › peer-review

Mediators of Obesity Do Not Influence SARS-CoV-2 Infection or Activation of Primary Human Lung Microvascular Endothelial Cells In Vitro

Ter Ellen, B. M., Niewold, J., Flikweert, A., Muller Kobold, A. C., Heeringa, P., van Meurs, M., Smit, J. M., van der Voort, P. H. J., Rodenhuis-Zybert, I. A. & Moser, J., 28-Jun-2022, In: Frontiers in Immunology. 13, 11 p., 879033.

Research output: Contribution to journal › Article › Academic › peer-review

Moxidectin and ivermectin inhibit sars-cov-2 replication in vero e6 cells but not in human primary airway epithelium cells

Dinesh Kumar, N., Ter Ellen, B. M., Bouma, E. M., Troost, B., van de Pol, D. P. I., van der Ende-Metselaar, H. H., van Gosliga, D., Apperloo, L., Carpaij, O. A., van den Berge, M., Nawijn, M. C., Stienstra, Y., Rodenhuis-Zybert, I. A. & Smit, J. M., 18-Jan-2022, In: Antimicrobial Agents and Chemotherapy. 66, 1, 26 p., e01543-21.

Research output: Contribution to journal › Article › Academic › peer-review

The COVID HOME study research protocol: Prospective cohort study of non-hospitalised COVID-19 patients

Tami, A., van der Gun, B. T. F., Wold, K. I., Vincenti-González, M. F., Veloo, A. C. M., Knoester, M., Harmsma, V. P. R., de Boer, G. C., Huckriede, A. L. W., Pantano, D., Gard, L., Rodenhuis-Zybert, I. A., Upasani, V., Smit, J., Dijkstra, A. E., de Haan, J. J., van Elst, J. M., van den Boogaard, J., O’ Boyle, S. & Nacul, L.& 2 others, Niesters, H. G. M. & Friedrich, A. W., Nov-2022, In: PLoS ONE. 17, 11, 19 p., e0273599.

Research output: Contribution to journal › Article › Academic › peer-review

TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to non-infectious immature dengue virus particles

Aguilar Briseño, J. A., Ramos Pereira, L., van der Laan, M., Pauzuolis, M., Ter Ellen, B. M., Upasani, V., Moser, J., de Souza Ferreira, L. C., Smit, J. M. & Rodenhuis-Zybert, I. A., 14-Oct-2022, In: PLoS Pathogens. 18, 10, 25 p., e1010499.

Research output: Contribution to journal › Article › Academic › peer-review

All (43) publications

Press/media

Wat gebeurt er als je meerdere virussen tegelijk krijgt?

Zybert, I.

30/01/2023

Press/Media: Expert Comment › Popular

What happens if you get several viruses at the same time? | Health

Zybert, I.

25/01/2023

Press/Media: Expert Comment › Popular

Wat gebeurt er als je meerdere virussen tegelijk krijgt?

Zybert, I.

25/01/2023

Press/Media: Expert Comment › Popular

All (3) press/media

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