prof. dr. G. (Gerald) de Haan

Professor

Faculty of Medical Sciences

Telephone:

+31 50 361 7300 (Secretariat)

+31 50 361 7310 (fax)

E-mail:

g.de.haan umcg.nl

ORCID Research Portal

Publications

CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal

Skinder, N., Sanz Fernández, I., Dethmers-Ausema, A., Weersing, E. & de Haan, G., 9-Jan-2024, In: Blood Advances. 8, 1, p. 99-111 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

How CBX proteins regulate normal and leukemic blood cells

de Groot, A. P. & de Haan, G., 2024, In: FEBS Letters. 19 p.

Research output: Contribution to journal › Review article › peer-review

3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice

Guerrero, A., Innes, A. J., Roux, P. F., Buisman, S. C., Jung, J., Ortet, L., Moiseeva, V., Wagner, V., Robinson, L., Ausema, A., Potapova, A., Perdiguero, E., Weersing, E., Aarts, M., Martin, N., Wuestefeld, T., Muñoz-Cánoves, P., de Haan, G., Bischof, O. & Gil, J., Sept-2022, In: Nature Aging. 2, 9, p. 851-866 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Role of quiescent cells in the homeostatic maintenance of the adult submandibular salivary gland

Serrano Martinez, P., Maimets, M., Bron, R., van Os, R., de Haan, G., Pringle, S. & Coppes, R. P., 21-Oct-2022, In: iScience . 25, 10, 105047.

Research output: Contribution to journal › Article › Academic › peer-review

Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity

Kim, K. M., Mura-Meszaros, A., Tollot, M., Krishnan, M. S., Grundl, M., Neubert, L., Groth, M., Rodriguez-Fraticelli, A., Svendsen, A. F., Campaner, S., Andreas, N., Kamradt, T., Hoffmann, S., Camargo, F. D., Heidel, F. H., Bystrykh, L., de Haan, G. & von Eyss, B., 3-Sept-2022, In: Nature Communications. 13, 1, 16 p., 5187.

Research output: Contribution to journal › Article › Academic › peer-review

The developmental stage of the medulloblastoma cell-of-origin restricts Hedgehog pathway usage and drug sensitivity

Smit, M. J., Martini, T. E. I., Armandari, I., Bočkaj, I., Zomerman, W. W., de Camargo Magalhães, E. S., Siragna, Z., Meeuwsen, T. G. J., Scherpen, F. J. G., Schoots, M. H., Ritsema, M., den Dunnen, W. F. A., Hoving, E. W., Paridaen, J. T. M. L., de Haan, G., Guryev, V. & Bruggeman, S. W. M., Jun-2022, In: Journal of Cell Science. 135, 11, 14 p., jeb258608.

Research output: Contribution to journal › Article › Academic › peer-review

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Svendsen, A. F., Yang, D., Kim, K. M., Lazare, S. S., Skinder, N., Zwart, E., Mura-Meszaros, A., Ausema, A., Eyss, B. V., de Haan, G. & Bystrykh, L. V., 12-Aug-2021, In: Blood. 138, 6, p. 439-451 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Inflammation and Aging of Hematopoietic Stem Cells in Their Niche

Yang, D. & de Haan, G., 21-Jul-2021, In: Cells. 10, 8, 13 p., 1849.

Research output: Contribution to journal › Review article › peer-review

Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response

Serrano Martinez, P., Cinat, D., van Luijk, P., Baanstra, M., de Haan, G., Pringle, S. & Coppes, R. P., Jan-2021, In: Oral diseases. 1, p. 52-63 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1

Renders, S., Svendsen, A. F., Panten, J., Rama, N., Maryanovich, M., Sommerkamp, P., Ladel, L., Redavid, A. R., Gibert, B., Lazare, S., Ducarouge, B., Schönberger, K., Narr, A., Tourbez, M., Dethmers-Ausema, B., Zwart, E., Hotz-Wagenblatt, A., Zhang, D., Korn, C. & Zeisberger, P.& 12 others, Przybylla, A., Sohn, M., Mendez-Ferrer, S., Heikenwälder, M., Brune, M., Klimmeck, D., Bystrykh, L., Frenette, P. S., Mehlen, P., de Haan, G., Cabezas-Wallscheid, N. & Trumpp, A., 27-Jan-2021, In: Nature Communications. 12, 1, 15 p., 608.

Research output: Contribution to journal › Article › Academic › peer-review