B.M. (Bente) Hofstra

Faculty of Medical Sciences

Telephone:

E-mail:

b.m.hofstra umcg.nl

ORCID Research Portal

Research interests

PhD project: Hippocampal functioning as a link between depression and Alzheimer's disease

Publications

Comprehensive analysis of genetic risk loci uncovers novel candidate genes and pathways in the comorbidity between depression and Alzheimer's disease

Hofstra, B. M., Kas, M. J. H. & Verbeek, D. S., 11-Jun-2024, In: Translational Psychiatry. 14, 1, 8 p., 253.

Research output: Contribution to journal › Article › Academic › peer-review

Cross-species analysis uncovers the mitochondrial stress response in the hippocampus as a shared mechanism in mouse early life stress and human depression

Hofstra, B. M., Hoeksema, E. E., Kas, M. J. & Verbeek, D. S., Jul-2024, In: Neurobiology of stress. 31, 9 p., 100643.

Research output: Contribution to journal › Article › Academic › peer-review

Exploring the overlapping genetic and molecular hippocampal mechanisms between Alzheimer’s disease and depression

Hofstra, B. M., 2024, [Groningen]: University of Groningen. 177 p.

Research output: Thesis › Thesis fully internal (DIV)

Antisense oligonucleotide therapeutic approach for suppression of Ataxin-1 expression: A safety assessment

O'Callaghan, B., Hofstra, B., Handler, H. P., Kordasiewicz, H. B., Cole, T., Duvick, L., Friedrich, J., Rainwater, O., Yang, P., Benneyworth, M., Nichols-Meade, T., Heal, W., Ter Haar, R., Henzler, C. & Orr, H. T., 4-Sept-2020, In: Molecular therapy - Nucleic acids. 21, p. 1006-1016 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles

Friedrich, J., Kordasiewicz, H. B., O'Callaghan, B., Handler, H. P., Wagener, C., Duvick, L., Swayze, E. E., Rainwater, O., Hofstra, B., Benneyworth, M., Nichols-Meade, T., Yang, P., Chen, Z., Ortiz, J. P., Clark, H. B., Öz, G., Larson, S., Zoghbi, H. Y., Henzler, C. & Orr, H. T., 2-Nov-2018, In: JCI Insight. 3, 21, 18 p., e123193.

Research output: Contribution to journal › Article › Academic › peer-review

All (5) publications

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