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A. Osipyan, MSc

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Faculty of Science and Engineering

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a.osipyan rug.nl

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Publications

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

Chen, D., Osipyan, A., Adriana, J., Kader, M., Gureev, M., Knol, C. W. J., Sigmund, M. C., Xiao, Z., van der Wouden, P. E., Cool, R. H., Poelarends, G. J. & Dekker, F. J., 13-Jul-2023, In: Journal of Medicinal Chemistry. 66, 13, p. 8767-8781 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Design and synthesis of ligands targeting MIF family enzymes and their application in medicinal chemistry

Osipyan, A., 2023, [Groningen]: University of Groningen. 135 p.

Research output: Thesis › Thesis fully internal (DIV)

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 10-Feb-2022, In: Journal of Medicinal Chemistry. 65, 3, p. 2059-2077

Research output: Contribution to journal › Article › Academic › peer-review

Epigenetic regulation in macrophage migration inhibitory factor (MIF)-mediated signaling in cancer and inflammation

Osipyan, A., Chen, D. & Dekker, F. J., Jul-2021, In: Drug Discovery Today. 26, 7, p. 1728-1734

Research output: Contribution to journal › Review article › peer-review

Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines

Osipyan, A., Shaabani, S., Warmerdam, R., Shishkina, S. V., Boltz, H. & Dömling, A., 20-Jul-2020, In: Angewandte Chemie (International ed. in English). 59, 30, p. 12423-12427

Research output: Contribution to journal › Article › Academic › peer-review

Correction to Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

Wang, Q., Osipyan, A., Konstantinidou, M., Butera, R., Mgimpatsang, K. C., Shishkina, S. V. & Dömling, A., 19-Jun-2020, In: The Journal of Organic Chemistry. 85, 12, p. 8295 1 p., 8295.

Research output: Contribution to journal › Erratum

Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles

Wang, Q., Osipyan, A., Konstantinidou, M., Butera, R., Mgimpatsang, K. C., Shishkina, S. V. & Dömling, A., 20-Sept-2019, In: The Journal of Organic Chemistry. 84, 18, p. 12148-12156 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Rethinking Hydrolytic Imidazoline Ring Expansion: A Common Approach to the Preparation of Medium-Sized Rings via Side-Chain Insertion into [1.4]Oxa- and [1.4]Thiazepinone Scaffolds

Reutskaya, E., Osipyan, A., Sapegin, A., Noyikov, A. S. & Krasavin, M., 15-Feb-2019, In: Journal of Organic Chemistry. 84, 4, p. 1693-1705 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (8) publications

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