A mouse tissue transcription factor atlas
Transcription factors (TFs) drive various biological processes ranging from embryonic development to carcinogenesis. Here, the group of Zhou and Qin developed a concatenated tandem array of consensus TF response elements (catTFRE) approach to profile the activated TFs in 24 adult and 8 fetal mouse tissues on proteome scale. This study provides a landscape of TFs in mouse tissues that can be used to elucidate transcriptional regulatory specificity and programming and as a baseline that may facilitate understanding diseases that are regulated by TFs.
More :Nature Communications
| Last modified: | 25 April 2017 11.46 a.m. |
More news
-
16 December 2024
Jouke de Vries: ‘The University will have to be flexible’
2024 was a festive year for the University of Groningen. Jouke de Vries, the chair of the Executive Board, looks back.
-
10 June 2024
Swarming around a skyscraper
Every two weeks, UG Makers puts the spotlight on a researcher who has created something tangible, ranging from homemade measuring equipment for academic research to small or larger products that can change our daily lives. That is how UG...
-