Publicaties 2005

de Kanter R, Tuin A, van de Kerkhof E, Martignoni M, Draaisma AL, de Jager MH, de Graaf IAM, Meijer DKF, Groothuis GMM . A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies. Journal of Pharmacological and Toxicological Methods, 2005; 51(1):65-72. DOI

Yan X, Kuipers F, Havekes LM, Havinga R, Dontje B, Poelstra K, Scherphof GL, Kamps JAAM. The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse. Biochemical andBiophysical Research Communications, 2005; 328(1):57-62. DOI
Notes: Erratum appeared in volume 330 (2005) , pp. 1320  DOI

Prakash J, van Loenen-Weemaes AM, Haas M, Proost JH, Meijer DKF, Moolenaar F, Poelstra K, Kok RJ. Renal-selective delivery and angiotensin-coverting enzyme inhibition by subcutaneously administered captopril-lysozyme. Drug Metabolism and Disposition, 2005; 33(5):683-688. DOI

Kuldo JM, Ogawara KI, Werner N, Ásgeirsdóttir SA, Kamps JAAM, Kok RJ, Molema G. Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases. Current Vascular Pharmacology, 2005; 3(1):11-39. DOI

Waarts BL, Aneke OJC, Smit JM, Kimata K, Bittman R, Meijer DKF, Wilschut J.  Antiviral activity of human lactoferrin: inhibition of alphavirus interaction with heparan sulfate. Virology, 2005; 333(2):284-292. DOI

Olinga P, van der Hoeven JAB, Merema MT, Freund RL, Ploeg RJ, Groothuis GMM . The influence of brain death on liver function. Liver International, 2005; 25(1):109-116. DOI

Couvreur P, Braguer D, Crommelin DJA, Duchêne D, Engels JW, Kerr DJ, Krogsgaard-Larsen P, Meijer DKF, Paoletti R, Wagner E. EUFEPS report. Contribution of academic research to discovery and development of medicines: current status and future opportunities. European Journal of Pharmaceutical Sciences, 2005; 24(2-3):245-252. DOI

Prakash J, Saluja V, Visser J, Moolenaar F, Meijer DKF, Poelstra K, Kok RJ.  Bioanalysis and pharmacokinetics of the p38 MAPkinase inhibitor SB202190 in rats. Journal of Chromatography B, 2005; 826(1-2):220-225. DOI

Greupink R, Bakker HI, Reker-Smit C, van Loenen-Weemaes AM, Kok RJ, Meijer DKF, Beljaars L, Poelstra K . Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell. Journal of Hepatology, 2005; 43(5):884-892. DOI

Hofmann AF, Zakko SF, Lira M, Clerici C, Hagey LR, Lambert KK, Steinbach JH, Schteingart CD, Olinga P, Groothuis GMM. Novel biotransformation and physiological properties of norursodeoxycholic acid in humans. Hepatology, 2005; 42(6):1391-1398. DOI

van de Bovenkamp M, Groothuis GMM, Draaisma AL, Merema MT, Bezuijen JI, van Gils MJ, Meijer DKF, Friedman SL, Olinga P. Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu. Toxicological Sciences, 2005; 85(1):632-638. DOI

van de Kerkhof EG, de Graaf IAM, de Jager MH, Meijer DKF, Groothuis GMM . Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies. Drug Metabolism and Disposition, 2005; 33(11):1613-1620. DOI

Koudstaal LG, 't Hart NA, van den Berg A, Olinga P, van Goor H, Ploeg RJ, Leuvenink HGD.   Brain death causes structural and inflammatory changes in donor intestine. Transplantation Proceedings, 2005; 37(1):448-449. DOI

't Hart NA, van der Plaats A, Faber A, Leuvenink HGD, Olinga P, Wiersema-Buist J, Verkerke GJ, Rakhorst G, Ploeg RJ.  Oxygenation during hypothermic rat liver preservation: an in vitro slice study to demonstrate beneficial or toxic oxygenation effects. Liver Transplantation, 2005; 11(11):1403-1411. DOI  

Kuldo JM, Westra J, Ásgeirsdóttir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC, Molema G. Differential effects of NF-kappa B and p38 MAPK inhibitors and combinations thereof on TNF- alpha- and IL-1 beta- induced proinflammatory status of endothelial cells in vitro. American Journal of Physiology-Cell Physiology, 2005; 289(5):C1229-C1239. DOI

Temming K, Schiffelers RM, Molema G, Kok RJ . RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature. Drug Resistance Updates, 2005; 8(6):381-402. DOI

Meijer DKF, Lennernäs H. EUFEPS conference on drug transporters at Copenhagen: integrative approaches in ADME research. European Journal of Pharmaceutical Sciences, 2005; 26(1):130-143. DOI

Bartsch M, Weeke-Klimp AH, Morselt HWM, Kimpfler A, Ásgeirsdóttir SA, Schubert R, Meijer DKF, Scherphof GL, Kamps JAAM . Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells. Molecular Pharmacology, 2005; 67(3):883-890. DOI

Bartsch M, Weeke-Klimp AH, Meijer DKF, Scherphof GL, Kamps JAAM . Cell-specific targeting of lipid-based carriers for ODN and DNA. Journal of Liposome Research, 2005; 15(1-2):59-92. DOI

Groothuis GMM. De darm: meer dan absorptie alleen. Pharmaceutisch Weekblad, 2005; 140(10):328-332.

Poelstra K, Klein Haneveld J. Kennis en kunde: Klaas Poelstra onderzoekt drug targeting naar stellaatcellen. Pharmaceutisch Weekblad, 2005; 140(2):68-69.
Notes: Interview met K. Poelstra door J. Klein Haneveld, redacteur

Groothuis GMM. De Dierenexperimenten Commissie. Foliolum, 2005; 18(4):22-23.

Groothuis GMM. Werken met in vitro en humaanweefsel aan de RUG. Foliolum, 2005; 18(4):28-30.

Poelstra K. Ieder voordeel heeft z'n nadeel ; over het gebruik van proefdiermodellen in de praktijk. Foliolum, 2005; 18(4):24-27.

Adrian J. The adventure in Japan. GUIDElines, 2005;(44):7-9.

van de Kerkhof E. Ladies and gentlemen: it is time for exercise. GUIDElines, 2005;(44):12-13.
Notes: ULLA Summer School, 5-13 July 2005, Uppsala University, Sweden