Publications 2005

1.Boxma B, de Graaf RM, van der Staay GW, van Alen TA, Ricard G, Gabaldon T, van Hoek AH, Moon-van der Staay SY, Koopman WJ, van Hellemond JJ, Tielens AG, Friedrich T, Veenhuis M, Huynen MA, Hackstein JH. An anaerobic mitochondrion that produces hydrogen. Nature. 434:74-9.

2.Kiel JA, van der Klei IJ, van den Berg MA, Bovenberg RA, Veenhuis M. (2005) Overproduction of a single protein, Pc-Pex11p, results in 2-fold enhanced penicillin production by Penicillium chrysogenum. Fungal Genet Biol. 42:154-64.

3.Monastyrska I, van der Heide M, Krikken AM, Kiel JA, van der Klei IJ, Veenhuis M. (2005) Atg8 is essential for macropexophagy in Hansenula polymorpha. Traffic. 6:66-74.

4.Kiel, J.A.K.W., Emmrich, K., Meyer, H.E. and Kunau, W.H. (2005) Ubiquitination of the PTS1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import. J. Biol. Chem. 280:1921-1930

5.Kiel JA, Otzen M, Veenhuis M, van der Klei I.J. (2005) Obstruction of polyubiquitination affects PTS1 peroxisomal matrix protein import. Biochim Biophys Acta. 1745:176-86.

6.Otzen M, Wang D, Lunenborg MG, van der Klei IJ. (2005) Hansenula polymorpha Pex20p is an oligomer that binds the peroxisomal targeting signal 2 (PTS2). J Cell Sci. 118:3409-3418.

7.Dunn, W.A. Jr., Cregg, J.M., Kiel, J.A.K.W., Van der Klei, I.J., Oku, M., Sakai, Y., Sibirny, A.A., Stasyk, O.V. and Veenhuis, M. (2005) Pexophagy: The selective autophagy of peroxisomes. Autophagy. 1, 75-83.

8.Monastryska, I., Kiel, J.A.K.W., Krikken, A.M., Komduur, J.A., Veenhuis, M. and Van der Klei, I.J. (2005) The Hansenula polymorpha ATG25 gene encodes a novel coiled-coil protein that is required for macropexophagy. Autophagy 1, 92-100.

9.Gunkel, K., Veenhuis, M. and Van der Klei, I.J. (2005) Protein translocation machineries: How organelles bring in matrix proteins. FEMS Yeast Research, 5:1037-45.

10.Ozimek, P., Veenhuis, M. and Van der Klei, I.J. (2005) A complex peroxisomal, oligomeric flavoprotein. FEMS Yeast Research 5:975-983.

11.de Bruin EC, Duitman EH, de Boer AL, Veenhuis M, Bos IG, Hack CE. (2005) Pharmaceutical proteins from methylotrophic yeasts. Methods Mol Biol. 308:65-76.

12.Lutz, M.V., Bovenberg, R.A., van der Klei, I.J. and Veenhuis, M. (2005)Synthesis of Penicillium chrysogenum acetyl-CoA:isopenicillin N acyltransferase in Hansenula polymorpha: First step towards the introduction of a new metabolic pathway. FEMS Yeast Res. 5:1063-1067.

13.Gellissen, G., Kunze, G., Gaillardin, C., Cregg, J.M., Berardi, E., Veenhuis, M., van der Klei, I.J. (2005) New yeast expression platforms based on methylotrophic Hansenula polymorpha and Pichia pastoris and on dimorphic Arxula adeninivorans and Yarrowia lipolytica - A comparison. FEMS Yeast Res. 5:1079-1096

14.Blecha A, Zarschler K, Sjollema KA, Veenhuis M, Rodel G. (2005) Expression and cytosolic assembly of the S-layer fusion protein mSbsC-EGFP in eukaryotic cells. Microb Cell Fact. 4:28.

15.Stevens P, Monastyrska I, Leao-Helder AN, van der Klei IJ, Veenhuis M, Kiel JA. (2005) Hansenula polymorpha Vam7p is required for macropexophagy. FEMS Yeast Res. 5:985-97.

16.Lutz MV, Bovenberg RA, van der Klei IJ, Veenhuis M. (2005) Synthesis of Penicillium chrysogenum acetyl-CoA:isopenicillin N acyltransferase in Hansenula polymorpha: first step towards the introduction of a new metabolic pathway. FEMS Yeast Res. 5:1063-1067.

17.Haan, G.J., Baerends, R.J.S., Krikken, A.M., Otzen, M., Veenhuis, M., and Van der Klei, I.J. (2005) Re-assembly of peroxisomes in Hansenula polymorpha pex3 cells upon re-introduction of Pex3p involves the nuclear envelope. FEMS Yeast Research. In press.

18.Ozimek, P., Koetter, P., Veenhuis, M. and Van der Klei, I.J. (2005) Hansenula polymorpha and Saccharomyces cerevisiae Pex5p's recognize different, independent peroxisomal targeting signals in alcohol oxidase. FEBS Letters, in press.