2004 publications

Gwenny M. Fuhler, Gerlinde J. Knol, A. Lyndsay Drayer, Edo Vellenga. Impaired Interleukin-8 and GROa induced phosphorylation of extracellular signal-regulated kinase results in decreased migration of neutrophils from patients with Myelodysplasia. J. Leuk. Biol. in press

Houwerzijl EJ, Blom NR, van der Want JJ, Louwes H, Esselink MT, Smit JW, Vellenga E, de Wolf JT. Increased peripheral platelet destruction and caspase-3-independent programmed cell death of bone marrow megakaryoctes in myelodysplastic patients. Blood. 2004 Nov 12; [Epub ahead of print]

Jan Jacob Schuringa, Kaida Wu, Giovanni Morrone, Malcolm A.S. Moore. Enforced Activation of STAT5A Facilitates the Generation of ES-Derived Hematopoietic Stem Cells That Contribute to Hematopoiesis In Vivo. Stem Cells. 2004;22(7):1191-204.

Schuringa JJ, Chung KY, Morrone G, Moore MA. Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation. J Exp Med. 2004 Sep 6;200(5):623-35

Chung KY, Morrone G, Schuringa JJ, Wong B, Dorn DC, Moore MA. Enforced expression of a Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis. Blood. 2004 Jul 8 [Epub ahead of print]

Heijink IH, Van Den Berge M, Vellenga E, De Monchy JG, Postma DS, Kauffman HF. Altered beta-adrenergic regulation of T cell activity after allergen challenge in asthma. Clin Exp Allergy. 2004 Sep;34(9):1356-63.

Brada SJ, van de Loosdrecht AA, Koudstaal J, de Wolf JT, Vellenga E. Limited numbers of apoptotic cells in fresh paraffin embedded bone marrow samples of patients with myelodysplastic syndrome. Leuk Res. 2004 Sep;28(9):921-5.

Sanz MA, Vellenga E, Rayon C, Diaz-Mediavilla J, Rivas C, Amutio E, Arias J, Deben G, Novo A, Bergua J, De La Serna J, Bueno J, Negri S, Beltran De Heredia JM, Martin G. All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. Blood. 2004 Aug 3 [Epub ahead of print]

Fuhler GM, Cadwallader KA, Knol GJ, Chilvers ER, Drayer AL, Vellenga E. Disturbed granulocyte macrophage-colony stimulating factor priming of phosphatidylinositol 3,4,5-trisphosphate accumulation and Rac activation in fMLP-stimulated neutrophils from patients with myelodysplasia. J Leukoc Biol. 2004 Jul;76(1):254-62. Epub 2004 Apr 23.

Houwerzijl EJ, Blom NR, van der Want JJ, Esselink MT, Koornstra JJ, Smit JW, Louwes H, Vellenga E, de Wolf JT. Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura. Blood. 2004 Jan 15;103(2):500-6.

Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E.Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway. Leukemia. 2004 Jan;18(1):103-12