Dineke Verbeek, PhD

MSc in Medical Biology, University of Utrecht, 2000
PhD thesis: The localization and identification of novel SCA genes in the Dutch autosomal dominant cerebellar ataxia population, Utrecht University, 2005

News

• August 2024: Appointed professor of scientific research in education
• August 2023: Appointed adjunct program director of medicine (bachelor and master) (FMS)
• January 2021: Appointed adjunct director of MSc Biomedical Sciences (FSE)

See all my papers in PubMed or in Google Scholar
Phone: + 31 (0)6 52724553
Email

Keywords: Neurogenetics, neuroscience, gene-editing, (medical) education, professional identity formation, physician-scientist

Dineke Verbeek is the main investigator of the neurogenetics group of the Department of Genetics. Her research centers on functional neurogenetics, with a focus on rare movement disorders. The work aims to understand the genetic, molecular and cellular mechanisms that underlie rare movement disorders using state-of-the-art technologies, including gene-editing techniques such as prime-editing, long-read sequencing and iPSC disease modelling. She is also a member of the Movement Disorders Groningen expertise center (Movement Disorders Groningen).

Dineke was appointed Professor of Scientific Research in Medical Education as of 1 August 2024. The field of scientific research in medical education focuses on incorporating biomedical research and scientific methodology into the curriculum of higher education institutions. This involves developing programs and courses that prepare students to understand, conduct and contribute to biomedical research. The field also aims to promote interdisciplinary collaboration between students and faculty in biology, biomedical science, medicine, nursing, pharmacy and other relevant disciplines. The ultimate goal is to educate students as evidence-based professionals who are capable of contributing to groundbreaking biomedical research and improving healthcare. This research is embedded in the de LEARN program ‘Lifeling Leaerning, Education and Assessment Research Network (LEARN - Lifelong Learning, Education and Assessment Research Network).

Within the Faculty of Medical Sciences, Dineke is currently the adjunct program director of medicine (bachelor and master). Additionally, she is a member of the advisory committee for the JSM/MD-PhD/Mandema programs of the UMCG. Dineke successfully obtained her Senior Teaching Qualification in 2023. She has been coordinator of various education modules within the Biomedical Sciences and Molecular Medicine Innovative Treatment program. She was the program director of MSc Biomedical Sciences of the Faculty of Science & Engineering for several years and has participated in a number of steering committees to improve current education.

Most recent publications

Identification and Copy Number Variant Analysis of Enhancer Regions of Genes Causing Spinocerebellar Ataxia. Ghorbani F, de Boer EN, Fokkens MR, de Boer-Bergsma J, Verschuuren-Bemelmans CC, Wierenga E, Kasaei H, Noordermeer D, Verbeek DS, Westers H, van Diemen CC.Int J Mol Sci. 2024 Oct 18;25(20):11205. doi: 10.3390/ijms252011205.PMID: 39456985 Free PMC article.

Comprehensive analysis of genetic risk loci uncovers novel candidate genes and pathways in the comorbidity between depression and Alzheimer's disease. Hofstra BM, Kas MJH, Verbeek DS. Transl Psychiatry. 2024 Jun 11;14(1):253. doi: 10.1038/s41398-024-02968-y.PMID: 38862462 Free PMC article.

Cross-species analysis uncovers the mitochondrial stress response in the hippocampus as a shared mechanism in mouse early life stress and human depression. Hofstra BM, Hoeksema EE, Kas MJ, Verbeek DS. Neurobiol Stress. 2024 May 14;31:100643. doi: 10.1016/j.ynstr.2024.100643. eCollection 2024 Jul.PMID: 38800537 Free PMC article.

Pathogenetic Insights into Developmental Coordination Disorder Reveal Substantial Overlap with Movement Disorders. Garofalo M, Vansenne F, Sival DA, Verbeek DS. Brain Sci. 2023 Nov 23;13(12):1625. doi: 10.3390/brainsci13121625.PMID: 38137073 Free PMC article.

See all Dineke Verbeek’s papers in Google Scholar or Pubmed