Prof. Amalia Dolga receives grant from Stichting Parkinson Fonds
Early this year, Prof. Amalia Dolga of the Groningen Research Institute of Pharmacy ( GRIP ) has been awarded a research grant from Stichting Parkinson Fonds of EUR 250,000. In the awarded project, postdoc Angelica Sabogal Guaqueta , in collaboration with co-PI’s Prof. Arjan Kortholt ( GBB ) and Prof. Sabeth Verpoorte ( GRIP ) will investigate how miscommunication between neurons and microglia affect the pathology of Parkinson’s disease.
The team combines the expertise of the Dolga lab (iPSC differentiation into brain cells, including neurons and microglia, mitochondrial and LRRK2 biology), the Kortholt lab (LRRK2 biochemistry, tools and structure) and the Verpoorte lab (microfluidics for organ-on-a-chip) to characterize the role of LRRK2 mutations in differentiated microglia and neurons obtained from PD patients. Using linked microchambers in a microfluidic device, they will investigate whether the activity of LRRK2 could affect neuron-microglia communication.

Last modified: | 14 March 2024 09.52 a.m. |
More news
-
25 April 2025
Leading microbiologist Arnold Driessen honoured
On 25 April 2025, Arnold Driessen (Horst, the Netherlands, 1958) received a Royal Decoration. Driessen is Professor of Molecular Microbiology and chair of the Molecular Microbiology research department of the Faculty of Science and Engineering at the...
-
24 April 2025
Highlighted papers April 2025
The antimalarial drug mefloquine could help treat genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy, as well as some cancers.
-
22 April 2025
Microplastics and their effects on the human body
Professor of Respiratory Immunology Barbro Melgert has discovered how microplastics affect the lungs and can explain how to reduce our exposure.