Nollen, Prof. Ellen
Nollen, a medical geneticist, researches the genetic source of the development of neurodegenerative diseases like Parkinson’s, Alzheimer’s and Huntington’s within the framework of the Healthy Ageing programme. She has previously conducted research into this at Northwestern University in Chicago (US) and at the Hubrecht Laboratory, the Ronald Plasterk’s KNAW institute in Utrecht. Nollen discovered that the moag-4 gene regulates the aggregation and harmful effects of disease proteins during the process of cell ageing.
Ellen Nollen was the first female researcher to be awarded a Rosalind Franklin Fellowship at the UMCG. The University of Groningen and the UMCG set up the Rosalind Franklin Fellowships to attract talented female researchers. In 2011 she was awarded a EUR 1.5 million European ERC grant for her research. The ERC grants are intended to further reinforce outstanding research teams.
More video's
- Nieuw onderzoeksentrum in UMCG (Dutch NOS Journaal)
- Meet ERIBA: Ellen Nollen
Previously in the news
-
How does the RUG keep women on board (Ukrant 25 March '19)
See also
-
'Ik wil weten hoe het zit' [I want to know what’s going on] (interview with Ellen Nollen, University of Groningen Annual Review 2009)
Contact and further information
2024
Koopman,
M., Güngördü, L., Janssen,
L., Seinstra, R. I., Richmond, J. E., Okerlund,
N., Wardenaar, R., Islam, P., Hogewerf,
W., Brown, A. E. X., Jorgensen, E. M., & Nollen,
E. A. A. (2024). Rebalancing the motor circuit
restores movement in a Caenorhabditis elegans model for TDP-43
toxicity. Cell reports,
43(5), Article 114204. https://doi.org/10.1016/j.celrep.2024.114204
2023
Stroo,
E., Janssen, L., Sin, O., Hogewerf, W.,
Koster, M., Harkema, L., Youssef, S. A., Beschorner, N.,
Wolters, A. H. G., Bakker, B., Becker, L.,
Garrett, L., Marschall, S., Hoelter, S. M., Wurst, W., Fuchs, H.,
Gailus-Durner, V., Hrabe de Angelis, M., Thathiah, A., ...
Nollen, E. A. A. (2023). Deletion of SERF2 in mice
delays embryonic development and alters amyloid deposit structure
in the brain. Life science alliance,
6(7), Article e202201730. https://doi.org/10.26508/lsa.202201730
Koopman,
M., Güngördü, L.,
Seinstra, R. I., & Nollen, E. A. A. (2023).
Neuronal overexpression of hTDP-43 in Caenorhabditis elegans
impairs different neuronally controlled behaviors anddecreases
fecundity. microPublication biology,
2023. Advance online publication. https://doi.org/10.17912/micropub.biology.000769
Koopman,
M., Güngördü, L.,
Seinstra, R. I., & Nollen, E. A. A. (2023).
Neuronal overexpression of hTDP-43 in Caenorhabditis elegans
impairs motor function. microPublication
biology, 2023. Advance online publication. https://doi.org/10.17912/micropub.biology.000768
Koopman,
M., Güngördü, L.,
Seinstra, R. I., Hogewerf, W., &
Nollen, E. A. A. (2023). Neuronal overexpression of
hTDP-43 in Caenorhabditis elegans mimics the cellular pathology
commonly observed in TDP-43 proteinopathies.
microPublication biology, 2023.
Advance online publication. https://doi.org/10.17912/micropub.biology.000767
Koopman,
M., Güngördü, L.,
Seinstra, R. I., & Nollen, E. A. A. (2023).
Neuronal overexpression of human TDP-43 in Caenorhabditis
elegans causes a range of sensorimotor phenotypes.
microPublication biology, 2023.
Advance online publication. https://doi.org/10.17912/micropub.biology.000766
2022
Broekmans,
S. A., Tornero, C. V., Toonen, L., Valls, M., Erbrink, R.,
Ronde, K. E., Hogewerf, W., Tolsma, L. E.
D., Seinstra, R. I., Janssen, L. L.
S., Nollen, E. A. A., & Valles, A. (2022).
Alpha-Synuclein Lowering and Rescue of Motor Phenotype by
miRNA-Based AAV Gene Therapy in In Vivo Parkinson's Disease
Models. Molecular Therapy,
30(4), 10-10.
Couzijn,
S., & Nollen, E. A. (2022). A sudden
collapse: the disaggregation of amyloid fibres.
The EMBO Journal, 41, Article
e111700. https://doi.org/10.15252/embj.2022111700
2021
Koopman,
M., Janssen, L., & Nollen, E. A.
A. (2021). An economical and highly adaptable
optogenetics system for individual and population-level
manipulation of Caenorhabditis elegans. BMC
Biology, 19(1), 170. https://doi.org/10.1186/s12915-021-01085-2
Perni,
M., van der Goot, A., Limbocker, R., van Ham, T. J., Aprile, F. A.,
Xu, C. K., Flagmeier, P., Thijssen, K., Sormanni, P., Fusco, G.,
Chen, S. W., Challa, P. K., Kirkegaard, J. B., Laine, R. F.,
Ma, K. Y., Müller, M. B. D., Sinnige, T., Kumita, J.
R., Cohen, S. I. A., ... Dobson, C. M. (2021). Comparative
Studies in the A30P and A53T α-Synuclein C. elegans Strains to
Investigate the Molecular Origins of Parkinson's Disease.
Frontiers in Cell and Developmental Biology,
9, Article 552549. https://doi.org/10.3389/fcell.2021.552549
Hardenberg,
M. C., Sinnige, T., Casford, S., Dada, S., Poudel, C., Robinson, E.
A., Fuxreiter, M., Kaminksi, C., Kaminski-Schierle, G. S.,
Nollen, E. A. A., Dobson, C. M., & Vendruscolo, M.
(2021). Observation of an α-synuclein liquid droplet
state and its maturation into Lewy body-like assemblies.
Journal of Molecular Cell Biology,
13(4), 282-294. https://doi.org/10.1093/jmcb/mjaa075
Koopman,
M., Janssen, L., & Nollen, E. A.
A. (2021). Publisher Correction to: An economical and
highly adaptable optogenetics system for individual and
population-level manipulation of Caenorhabditis elegans.
BMC Biology, 19(1), Article 216. https://doi.org/10.1186/s12915-021-01152-8
Pras,
A., & Nollen, E. A. A. (2021). Regulation of
Age-Related Protein Toxicity. Frontiers in Cell
and Developmental Biology, 9, 1-15. Article
637084. https://doi.org/10.3389/fcell.2021.637084
Pras,
A., Houben, B., Aprile, F. A., Seinstra, R., Gallardo,
R., Janssen, L., Hogewerf, W., Gallrein,
C., De Vleeschouwer, M., Mata-Cabana, A., Koopman, M.,
Stroo, E., de Vries, M., Edwards, S. L., Kirstein, J., Vendruscolo,
M., Falsone, S. F., Rousseau, F., Schymkowitz, J., &
Nollen, E. A. A. (2021). The cellular modifier
MOAG-4/SERF drives amyloid formation through charge
complementation. The EMBO Journal,
40(21), Article e107568. https://doi.org/10.15252/embj.2020107568
2020
Koopman,
M., Peter, Q., Seinstra, R. I., Perni, M.,
Vendruscolo, M., Dobson, C. M., Knowles, T. P. J., &
Nollen, E. A. A. (2020). Assessing motor-related
phenotypes of Caenorhabditis elegans with the wide field-of-view
nematode tracking platform. Nature
protocols, 15(6), 2071-2106. https://doi.org/10.1038/s41596-020-0321-9
Sorgdrager,
F. J. H., van Der Ley, C. P., van Faassen, M., Calus,
E., Nollen, E. A., Kema, I. P., van
Dam, D., & De Deyn, P. P. (2020). The
Effect of Tryptophan 2,3-Dioxygenase Inhibition on Kynurenine
Metabolism and Cognitive Function in the APP23 Mouse Model of
Alzheimer's Disease. International journal of
tryptophan research, 13, Article
1178646920972657. https://doi.org/10.1177/1178646920972657
2019
Sorgdrager,
F. J. H., Vermeiren, Y., Van Faassen, H. J.
R., Van Der Ley, C. P., Nollen, E. A. A.,
Kema, I. P., & De Deyn, P. P. (2019).
Age- and Disease-Specific Changes of the Kynurenine Pathway
in Parkinson's and Alzheimer's Disease. Journal of
Neurochemistry, 151(5), 656-668. https://doi.org/10.1111/jnc.14843
Koopman,
M., Seinstra, R. I., & Nollen, E. A.
A. (2019). C. elegans as a Model for Synucleinopathies
and Other Neurodegenerative Diseases: Tools and Techniques.
In T. Bartels (Ed.), Alpha-Synuclein (pp. 93-112).
(Methods in Molecular Biology). https://doi.org/10.1007/978-1-4939-9124-2_9
Laine,
R. F., Sinnige, T., Ma, K. Y., Haack, A. J., Poudel, C., Gaida, P.,
Curry, N., Perni, M., Nollen, E. A. A., Dobson, C. M.,
Vendruscolo, M., Schierle, G. S. K., & Kaminski, C. F. (2019).
Fast Fluorescence Lifetime Imaging Reveals the Aggregation
Processes of alpha-Synuclein and Polyglutamine in Aging
Caenorhabditis elegans. ACS chemical
biology, 14(7), 1628-1636. https://doi.org/10.1021/acschembio.9b00354
Koopman,
M., Hetz, C., & Nollen, E. A. A. (2019).
Saved by the Matrix: UPR Independent Survival under ER
Stress. Cell, 179(6),
1246-1248. https://doi.org/10.1016/j.cell.2019.11.012
Janssens,
G. E., Lin, X.-X., Millan-Ariño, L., Kavšek, A., Sen,
I., Seinstra, R. I., Stroustrup, N., Nollen, E.
A. A., & Riedel, C. G. (2019).
Transcriptomics-Based Screening Identifies Pharmacological
Inhibition of Hsp90 as a Means to Defer Aging.
Cell reports, 27(2), 467-480.e6. https://doi.org/10.1016/j.celrep.2019.03.044
Platten,
M., Nollen, E. A. A., Röhrig, U. F., Fallarino,
F., & Opitz, C. A. (2019). Tryptophan metabolism as a
common therapeutic target in cancer, neurodegeneration and
beyond. Nature Reviews Drug Discovery,
18(8), 379-401. https://doi.org/10.1038/s41573-019-0016-5
Sorgdrager,
F. J. H., Naude, P. J. W., Kema, I. P., Nollen,
E. A., & De Deyn, P. P. (2019).
Tryptophan Metabolism in Inflammaging: From Biomarker to
Therapeutic Target. Frontiers in
Immunology, 10, Article 2565. https://doi.org/10.3389/fimmu.2019.02565
2018
Javer,
A., Currie, M., Lee, C. W., Hokanson, J., Li, K., Martineau, C. N.,
Yemini, E., Grundy, L. J., Li, C., Ch'ng, Q., Schafer, W. R.,
Nollen, E. A. A., Kerr, R., & Brown, A. E. X. (2018).
An open-source platform for analyzing and sharing
worm-behavior data. Nature Methods,
15(9), 645-646. https://doi.org/10.1038/s41592-018-0112-1
Perni,
M., Casford, S., Aprile, F. A., Nollen, E. A.,
Knowles, T. P. J., Vendruscolo, M., & Dobson, C. M. (2018).
Automated Behavioral Analysis of Large C. elegans Populations
Using a Wide Field-of-view Tracking Platform.
Journal of visualized experiments : JoVE,
(141), Article 58643. https://doi.org/10.3791/58643
Sinnige,
T., Laine, R. F., Ma, K. Y., Haack, A. J., Gaida, P., Curry, N.,
Perni, M., Nollen, E. A. A., Dobson, C. M.,
Vendruscolo, M., Schierle, G. S. K., & Kaminski, C. F. (2018).
Fast Fluorescence Lifetime Imaging for Longitudinal Studies
of Protein Aggregation in Living C. Elegans.
Biophysical Journal, 114(3),
350A.
Sin,
O., Mata-Cabana, A., Seinstra, R. I., &
Nollen, E. A. A. (2018). Filter Retardation Assay for
Detecting and Quantifying Polyglutamine Aggregates Using
Lysates. JMIR research protocols,
8(19), Article 3042. https://doi.org/10.21769/BioProtoc.3042
Perni,
M., Challa, P. K., Kirkegaard, J. B., Limbocker, R., Koopman,
M., Hardenberg, M. C., Sormanni, P., Mueller, T., Saar, K.
L., Roode, L. W. Y., Habchi, J., Vecchi, G., Fernando, N., Casford,
S., Nollen, E. A. A., Vendruscolo, M., Dobson, C. M.,
& Knowles, T. P. J. (2018). Massively parallel C elegans
tracking provides multi-dimensional fingerprints for phenotypic
discovery. Journal of Neuroscience
Methods, 306, 57-67. https://doi.org/10.1016/j.jneumeth.2018.02.005
Perni,
M., Flagmeier, P., Limbocker, R., Cascella, R., Aprile, F. A.,
Galvagnion, C., Heller, G. T., Meisl, G., Chen, S. W., Kumita, J.
R., Challa, P. K., Kirkegaard, J. B., Cohen, S. I. A., Mannini, B.,
Barbut, D., Nollen, E. A. A., Cecchi, C., Cremades,
N., Knowles, T. P. J., ... Dobson, C. M. (2018). Multistep
Inhibition of alpha-Synuclein Aggregation and Toxicity in Vitro and
in Vivo by Trodusquemine. ACS chemical
biology, 13(8), 2308-2319. https://doi.org/10.1021/acschembio.8b00466
Mata-Cabana,
A., Sin, O., Seinstra, R. I., & Nollen, E.
A. A. (2018). Nuclear/Cytoplasmic Fractionation of
Proteins from Caenorhabditis elegans. JMIR
research protocols, 8(20), Article 3053. https://doi.org/10.21769/BioProtoc.3053
2017
Perni,
M., Galvagnion, C., Maltsev, A., Meisl, G., Mueller, M. B. D.,
Challa, P. K., Kirkegaard, J. B., Flagmeier, P., Cohen, S. I. A.,
Cascella, R., Chen, S. W., Limboker, R., Sormanni, P., Heller, G.
T., Aprile, F. A., Cremades, N., Cecchi, C., Chiti, F.,
Nollen, E. A. A., ... Dobson, C. M. (2017). A natural
product inhibits the initiation of alpha-synuclein aggregation and
suppresses its toxicity. Proceedings of the
National Academy of Sciences of the United States of
America, 114(6), E1009-E1017. https://doi.org/10.1073/pnas.1610586114
Stroo,
E., Koopman, M., Nollen, E. A. A., &
Mata-Cabana, A. (2017). Cellular Regulation of Amyloid
Formation in Aging and Disease. Frontiers in
Neuroscience, 11, Article 64. https://doi.org/10.3389/fnins.2017.00064
Perni,
M., Galvagnion, C., Maltsev, A., Meisl, G., Mueller, M. B. D.,
Challa, P. K., Kirkegaard, J. B., Flagmeier, P., Cohen, S. I. A.,
Cascella, R., Chen, S. W., Limboker, R., Sormanni, P., Heller, G.
T., Aprile, F. A., Cremades, N., Cecchi, C., Chiti, F.,
Nollen, E. A. A., ... Dobson, C. M. (2017). Correction
for Perni et al., A natural product inhibits the initiation of
alpha-synuclein aggregation and suppresses its toxicity (vol 114,
pg E1009, 2017). Proceedings of the National
Academy of Science of the United States of America,
114(12), E2543-E2543. https://doi.org/10.1073/pnas.1701964114
Nollen,
E. A. A., & Michels, H. (2017). Cysteine dioxygenase inhibitors for prolonging the
lifespan of a subject. (Patent No. EP3251664). https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=3251664A1&KC=A1&FT=D&ND=3&date=20171206&DB=&locale=en_EP
Jansen,
I. E., Ye, H., Heetveld, S., Lechler, M. C., Michels, H.,
Seinstra, R. I., Lubbe, S. J., Drouet, V., Lesage, S.,
Majounie, E., Gibbs, J. R., Nalls, M. A., Ryten, M., Botia, J. A.,
Vandrovcova, J., Simon-Sanchez, J., Castillo-Lizardo, M., Rizzu,
P., Blauwendraat, C., ... International Parkinson’s Disease
Genetics Consortium (IPGDC) (2017). Discovery and functional
prioritization of Parkinson's disease candidate genes from
large-scale whole exome sequencing. Genome
Biology, 18(22). https://doi.org/10.1186/s13059-017-1147-9
Sin,
O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini,
M. A., Aprile, F. A., Seinstra, R. I., Stroo, E.,
Prins, R. W., Martineau, C. N., Wang, H. H., Hogewerf,
W., Steinhof, A., Wanker, E. E., Vendruscolo, M.,
Calkhoven, C. F., Reinke, V., Guryev, V.,
& Nollen, E. A. A. (2017). Identification of an
RNA Polymerase III Regulator Linked to Disease-Associated Protein
Aggregation. Molecular Cell,
65(6), 1096-1108. https://doi.org/10.1016/j.molcel.2017.02.022
Yoshimura,
Y., Holmberg, M. A., Kukic, P., Andersen, C. B., Mata-Cabana, A.,
Falsone, S. F., Vendruscolo, M., Nollen, E. A. A.,
& Mulder, F. A. A. (2017). MOAG-4 promotes the
aggregation of alpha-synuclein by competing with self-protective
electrostatic interactions. The Journal of
Biological Chemistry, 292(20), 8269-8278. https://doi.org/10.1074/jbc.M116.764886
2016
Habchi,
J., Arosio, P., Perni, M., Costa, A. R., Yagi-Utsumi, M., Joshi,
P., Chia, S., Cohen, S. I. A., Müller, M. B. D., Linse,
S., Nollen, E. A. A., Dobson, C. M., Knowles, T. P.
J., & Vendruscolo, M. (2016). An anticancer drug
suppresses the primary nucleation reaction that initiates the
production of the toxic Aβ42 aggregates linked with
Alzheimer's disease. Science Advances,
2(2), Article e1501244. https://doi.org/10.1126/sciadv.1501244
Koopman,
M., Michels, H., Dancy, B. M., Kamble, R., Mouchiroud, L.,
Auwerx, J., Nollen, E. A. A., & Houtkooper, R. H.
(2016). A screening-based platform for the assessment of
cellular respiration in Caenorhabditis elegans.
Nature protocols, 11(10), 1798-1816.
https://doi.org/10.1038/nprot.2016.106
Michels,
H., Seinstra, R. I., Uitdehaag, J. C. M.,
Koopman, M., van Faassen, M., Martineau, C.
N., Kema, I. P., Buijsman, R., & Nollen, E.
A. A. (2016). Identification of an evolutionary
conserved structural loop that is required for the enzymatic and
biological function of tryptophan 2,3-dioxygenase.
Scientific Reports, 6, Article
39199. https://doi.org/10.1038/srep39199
Visscher,
M., De Henau, S., Wildschut, M. H. E., van Es, R. J. J., Dhondt,
I., Michels, H., Kemmeren, P., Nollen, E. A.,
Braeckman, B. P., Burgering, B. M. T., Vos, H. R., & Dansen, T.
B. (2016). Proteome-wide Changes in Protein Turnover Rates in
C. elegans Models of Longevity and Age-Related Disease.
Cell reports, 16(11), 3041-3051. https://doi.org/10.1016/j.celrep.2016.08.025
2015
Srinivasan,
B., Baratashvili, M., van der Zwaag, M., Kanon,
B., Colombelli, C., Lambrechts, R. A., Schaap,
O., Nollen, E. A., Podgorsek, A., Kosec, G., Petkovic,
H., Hayflick, S., Tiranti, V., Reijngoud, D.-J.,
Grzeschik, N. A., & Sibon, O. C. M. (2015).
Extracellular 4 '-phosphopantetheine is a source for
intracellular coenzyme A synthesis. Nature
Chemical Biology, 11(10), 784-792.e3. https://doi.org/10.1038/NCHEMBIO.1906
Alvarenga
Fernandes Sin, O., & Nollen, E. A. A. (2015).
Regulation of protein homeostasis in neurodegenerative
diseases: the role of coding and non-coding genes.
Cellular and molecular life sciences,
72(21), 4027-4047. https://doi.org/10.1007/s00018-015-1985-0
2014
Alvarenga
Fernandes Sin, O., Michels, H., & Nollen, E. A. A.
(2014). Genetic screens in Caenorhabditis elegans models for
neurodegenerative diseases. Biochimica et
biophysica acta-Molecular basis of disease,
1842(10), 1951-1959. https://doi.org/10.1016/j.bbadis.2014.01.015
2013
Holmberg,
M., & Nollen, E. A. A. (2013). Analyzing
modifiers of protein aggregation in C. elegans by native agarose
gel electrophoresis. In D. M. Hatters, & A. J. Hannan
(Eds.), Tandem Repeats in Genes, Proteins, and Disease
(Vol. 1017, pp. 193-199). (Methods in Molecular Biology; Vol.
1017). Humana Press. https://doi.org/10.1007/978-1-62703-438-8_14
van
der Goot, A. T., & Nollen, E. A. A. (2013).
Tryptophan metabolism: entering the field of aging and
age-related pathologies. Trends in Molecular
Medicine, 19(6), 336-344. https://doi.org/10.1016/j.molmed.2013.02.007
2012
van
der Goot, A. T., Zhu, W., Vazquez-Manrique, R. P., Seinstra,
R. I., Dettmer, K., Michels, H., Farina, F., Krijnen, J.,
Melki, R., Buijsman, R. C., Silva, M. R., Thijssen, K. L.,
Kema, I. P., Neri, C., Oefner, P. J., & Nollen, E.
A. A. (2012). Delaying aging and the aging-associated
decline in protein homeostasis by inhibition of tryptophan
degradation. Proceedings of the National Academy
of Sciences of the United States of America,
109(37), 14912-14917. https://doi.org/10.1073/pnas.1203083109
Falsone,
S. F., Meyer, N. H., Schrank, E., Leitinger, G., Pham, C. L. L.,
Fodero-Tavoletti, M. T., Holmberg, M., Dulle, M., Scicluna, B.,
Gesslbauer, B., Rueckert, H.-M., Wagner, G. E., Merle, D. A.,
Nollen, E. A., Kungl, A. J., Hill, A. F., Cappai, R., &
Zangger, K. (2012). SERF Protein Is a Direct Modifier of
Amyloid Fiber Assembly. Cell reports,
2(2), 358-371. https://doi.org/10.1016/j.celrep.2012.06.012
2011
Schierle,
G. S. K., Bertoncini, C. W., Chan, F. T. S., van der Goot, A. T.,
Schwedler, S., Skepper, J., Schlachter, S., van Ham, T., Esposito,
A., Kumita, J. R., Nollen, E. A. A., Dobson, C. M.,
& Kaminski, C. F. (2011). A FRET Sensor for Non-Invasive
Imaging of Amyloid Formation in Vivo.
Chemphyschem, 12(3), 673-680. https://doi.org/10.1002/cphc.201000996
Siudeja,
K., Srinivasan, B., Xu, L., Rana, A., de Jong,
J., Nollen, E. A. A., Jackowski, S., Sanford,
L., Hayflick, S., & Sibon, O. C. M. (2011).
Impaired Coenzyme A metabolism affects histone and tubulin
acetylation in Drosophila and human cell models of pantothenate
kinase associated neurodegeneration. EMBO
Molecular Medicine, 3(12), 755-766. https://doi.org/10.1002/emmm.201100180
Teuling,
E., Bourgonje, A., Veenje, S., Thijssen, K., de Boer,
J., van der Velde, J., Swertz, M.,
& Nollen, E. (2011). Modifiers of mutant
huntingtin aggregation: Functional conservation of C.
elegans-modifiers of polyglutamine aggregation.
PLoS Currents, 3(RRN1255). https://doi.org/10.1371/currents.RRN1255
2010
van
Ham, T. J., Holmberg, M. A., van der Goot, A. T., Teuling,
E., Garcia-Arencibia, M., Kim, H., Du, D., Thijssen, K. L.,
Wiersma, M., Burggraaff, R., van Bergeijk, P., van Rheenen, J., van
Veluw, G. J., Hofstra, R. M. W., Rubinsztein, D. C., &
Nollen, E. A. A. (2010). Identification of MOAG-4/SERF
as a Regulator of Age-Related Proteotoxicity.
Cell, 142(4), 601-612. https://doi.org/10.1016/j.cell.2010.07.020
van
Ham, T. J., Esposito, A., Kumita, J. R., Hsu, S.-T. D., Schierle,
G. S. K., Kaminsk, C. F., Dobson, C. M., Nollen, E. A.
A., & Bertoncini, C. W. (2010). Towards
Multiparametric Fluorescent Imaging of Amyloid Formation: Studies
of a YFP Model of alpha-Synuclein Aggregation.
Journal of Molecular Biology,
395(3), 627-642. https://doi.org/10.1016/j.jmb.2009.10.066
2009
Roodveldt,
C., Bertoncini, C. W., Andersson, A., van der Goot, A. T., Hsu,
S.-T., Fernandez-Montesinos, R., de Jong, J., van Ham,
T. J., Nollen, E. A., Pozo, D., Christodoulou, J.,
& Dobson, C. M. (2009). Chaperone proteostasis in
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