Novel asymmetric copper-catalyzed transformations
PhD ceremony: Mr. P.H. Bos, 14.30 uur, Academiegebouw, Broerstraat 5, Groningen
Dissertation: Novel asymmetric copper-catalyzed transformations
Promotor(s): prof. B.L. Feringa
Faculty: Mathematics and Natural Sciences
As a consequence of the increased complexity of target molecules both in industry and academic research, the development of new methodology remains an important aspect of organic chemistry both in current time as well as for the future. Across the entire field of chemistry, from material science to pharmaceutical chemistry, efficient synthetic methods are crucial and of increasing importance, especially in the context of sustainable chemistry for the future. This thesis describes the development of a variety of novel asymmetric carbon-carbon bond forming reactions. All of the methods that were developed in this thesis rely on the use of catalytic amounts of chiral copper/ligand complexes in combination with organometallic reagents to establish asymmetric carbon-carbon bond formation with excellent enantiomeric excess.
Last modified: | 13 March 2020 01.00 a.m. |
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